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t(14;18)

A cytogenetic abnormality that involves a translocation between chromosomes 14 and 18.
National Institutes of Health

Related topics

Related topics

2 relations
Chromosomes, Human, Pair 14Chromosomes, Human, Pair 18

Papers overview

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Highly Cited
2008
Highly Cited
2008
C-MYC translocation in t(14;18) positive follicular lymphoma at presentation: An adverse prognostic indicator?
Follicular lymphoma (FL) is a common subtype of low grade B-cell non-Hodgkin lymphoma (NHL). Although this form of lymphoma often… 
Review
2002
Review
2002
Detection of BCL2 rearrangements in follicular lymphoma.
Review
2000
Review
2000
Molecular insights into the immunopathogenesis of follicular lymphoma.
Highly Cited
1997
Highly Cited
1997
The WT1 Protein Is a Negative Regulator of the Normalbcl-2 Allele in t(14;18) Lymphomas*
The translocated and normal bcl-2 alleles in the DHL-4 cell line with the t(14;18) translocation were separated by pulsed field… 
Highly Cited
1996
Highly Cited
1996
CREB Proteins Function as Positive Regulators of the Translocated bcl-2 Allele in t(14;18) Lymphomas*
The translocated and normal bcl-2 alleles in the DHL-4 cell line with the t(14;18) translocation were separated by pulsed field… 
Highly Cited
1993
Highly Cited
1993
Combination of t(14;18) and a Burkitt's type translocation in B-cell malignancies.
The combination of chromosomal translocations associated with bcl-2 rearrangement [t(14;18)] and c-myc rearrangement [t(8;14), t… 
Highly Cited
1992
Highly Cited
1992
Detection of the t(14;18) at similar frequencies in hyperplastic lymphoid tissues from American and Japanese patients.
Follicular lymphoma shows a wide geographic variation in incidence, occurring more frequently in the U.S. than in Japan. A… 
Review
1990
Review
1990
The 14;18 translocation in European cases of follicular lymphoma: comparison of Southern blotting and the polymerase chain reaction
Summary. The 14;18 chromosomal translocation is widely recognized as a cytogenetic abnormality associated with follicular… 
Review
1988
Review
1988
Chromosome studies in the non-Hodgkin's lymphomas: the role of the 14;18 translocation.
The 14;18 translocation [t(14;18)] is the most common chromosome abnormality noted in the non-Hodgkin's lymphomas (NHL). Although… 
Highly Cited
1984
Highly Cited
1984
Recurrent chromosomal defects are found in most patients with non-Hodgkin's-lymphoma.
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