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t(14;18)

A cytogenetic abnormality that involves a translocation between chromosomes 14 and 18.
National Institutes of Health

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2 relations
Chromosomes, Human, Pair 14Chromosomes, Human, Pair 18

Papers overview

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2016
2016
Transformation of follicular lymphoma into classical Hodgkin lymphoma showing t(14;18)
: Follicular lymphomas (FLs) are B-cell lymphomas with a generally indolent clinical course with the propensity to transform to… 
2010
2010
Study of t(14;18) chromosomal translocation and bcl-2 gene amplification in gastrointestinal diffuse large B-cell lymphoma
Objective To study the correlation between Bcl-2 gene abnormalities and the subclassification of gastrointestinal diffuse large B… 
2003
2003
6 q Deletions Define Distinct Clinico-Pathologic Subsets of Non-Hodgkin ’ s Lymphoma
Commonly observed in lymphoid neoplasms, deletions of 6q have been correlated with histologic and clinical subsets of non-Hodgkin… 
1999
1999
PCR Analysis for the t(14;18) Translocation in Patients With Recurrent Follicular Lymphoma Following Immunotherapy With Rituximab (IDEC-C2B8)
The chimeric monoclonal anti-CD20 antibody rituximab (Rituxan) has been shown to have clinical activity in patients with 
1998
1998
Polymerase Chain Reaction Diagnosis of t(14;18) From Paraffin‐Embedded Tissues Fixed With Holland Bouin Fluid
The t(14;18) translocation and its molecular counterpart, the bcl-2/lgH gene rearrangement, are highly characteristic of… 
1993
1993
Follicular center cell lymphoma with the t(14;18) translocation in which the rearranged BCL-2 gene is silent.
Using reverse transcription and the polymerase chain reaction (RT-PCR), we determined the level of expression of BCL-2/IgH in 18… 
1992
1992
The t(14;18) translocation in Hodgkin's disease.
In this issue of the Journal, Poppema et al. (7) contribute significantly to our understanding of the role of the t(14;18… 
1991
1991
Absence of t(14;18) major and minor breakpoints and of Bcl-2 protein overproduction in Reed-Sternberg cells of Hodgkin's disease.
The t(14;18) translocation, found in most human follicular non-Hodgkin's lymphomas (NHLs), juxtaposes the Bcl-2 oncogene at 18q21… 
Highly Cited
1991
Highly Cited
1991
Absence of bcl-2 major breakpoint region and JH gene rearrangement in lymphocyte predominance Hodgkin's disease. Results of Southern blot analysis and polymerase chain reaction.
Recent evidence suggests that nodular lymphocyte predominance Hodgkin's disease (NLPHD) is a distinct entity that may be related… 
1988
1988
Recent progress on the human bcl-2 gene involved in follicular lymphoma: characterization of the protein products.
Chromosome translocations involving the immunoglobulin heavy chain gene are common in B cell malignancies (Yunis 1983). The t(14…