t(14;16)

A chromosomal translocation that involves the chromosomes 14 and 16.
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
PURPOSE The clinical outcome of multiple myeloma (MM) is heterogeneous. A simple and reliable tool is needed to stratify patients… (More)
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Highly Cited
2012
Highly Cited
2012
Routine incorporation of FISH into multiple myeloma (MM) diagnostic testing has led to a better appreciation of the heterogeneity… (More)
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2011
2011
Many trials in myeloma are stratified on cytogenetic abnormalities. Among them, the most commonly chosen are the t(4;14), the del… (More)
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Highly Cited
2011
Highly Cited
2011
A panel of members of the 2009 International Myeloma Workshop developed guidelines for risk stratification in multiple myeloma… (More)
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Highly Cited
2010
Highly Cited
2010
To determine the effect of dexamethasone on the antimyeloma effects of lenalidomide, we tested in vitro proliferation, tumor… (More)
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Highly Cited
2010
Highly Cited
2010
Specific microRNA (miRNA) signatures have been associated with different cytogenetic subtypes in acute leukemias. This finding… (More)
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Highly Cited
2007
Highly Cited
2007
We performed fluorescent in situ hybridization (FISH) for 16q23 abnormalities in 861 patients with newly diagnosed multiple… (More)
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Highly Cited
2007
Highly Cited
2007
Clinical outcomes for multiple myeloma (MM) are highly heterogeneous and it is now clear that pivotal genetic events are the… (More)
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Highly Cited
2002
Highly Cited
2002
Multiple myeloma (MM) is a plasma-cell malignancy characterized by marked epidemiological, biological, and clinical heterogeneity… (More)
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Highly Cited
2001
Highly Cited
2001
Primary plasma cell leukemia (PCL) is a rare plasma cell malignancy. Consequently, few large reports have been published… (More)
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