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syncytium formation

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived… (More)
National Institutes of Health

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1962-2018
020406019622018

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syncytium formation by plasma membrane fusion

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1962-2018
1960198020002020
syncytium formation
syncytium formation by plasma membrane fusion

Papers overview

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2005
2005
RhoA signaling is required for respiratory syncytial virus-induced syncytium formation and filamentous virion morphology.
Respiratory syncytial virus (RSV) is an important human pathogen that can cause severe and life-threatening respiratory… (More)
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2005
2005
Extensive syncytium formation mediated by the reovirus FAST proteins triggers apoptosis-induced membrane instability.
The fusion-associated small transmembrane (FAST) proteins of the fusogenic reoviruses are the only known examples of membrane… (More)
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2003
2003
The central role of human chorionic gonadotropin in the formation of human placental syncytium.
A number of trophoblast products, including human chorionic gonadotropin (hCG), can increase the formation of human placental… (More)
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Highly Cited
1996
Highly Cited
1996
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1.
We have isolated and characterized human monoclonal antibody 2G12 to the gp120 surface glycoprotein of human immunodeficiency… (More)
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1996
1996
Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytes.
The V3 region of the human immunodeficiency virus type 1 (HIV-1) envelope protein is known to have a major influence on… (More)
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Highly Cited
1995
Highly Cited
1995
The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle.
Human immunodeficiency virus type 1 (HIV-1) infection causes profound immunological defects in afflicted patients. Various… (More)
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1989
1989
Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation.
Cell fusion (syncytium formation) is a major cytopathic effect of infection by human immunodeficiency virus (HIV) and may also… (More)
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Highly Cited
1988
Highly Cited
1988
A soluble CD4 protein selectively inhibits HIV replication and syncytium formation.
The CD4 (T4) molecule is expressed on a subset of T lymphocytes involved in class II MHC recognition, and is probably the… (More)
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1987
1987
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.
Human immunodeficiency virus (HIV), the causative agent of AIDS, infects human lymphocytes and monocytes. An interaction between… (More)
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Highly Cited
1986
Highly Cited
1986
Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity.
Acquired immune deficiency syndrome (AIDS) is characterized by marked depletion of the T4+ helper subset of T cells. The… (More)
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