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syncytin

Known as: syncytin-1, syncytin-1 protein, human, ERVWE1 protein 
National Institutes of Health

Related topics

Related topics

3 relations
ERVW-1 gene

Broader (2)

Gene Products, envPregnancy Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Human Endogenous Retroviral Envelope Protein Syncytin-1 and Inflammatory Abnormalities in Neuropsychological Diseases
Human endogenous retroviruses (HERVs) comprise approximately 8% of the human genome. Recent studies have considered HERVs as… 
Highly Cited
2014
Highly Cited
2014
Decreased expression and altered methylation of syncytin-1 gene in human placentas associated with preeclampsia.
Syncytin-1 is a protein coded by a human endogenous retrovirus (HERV) gene of the HERV-W family (HERVWE1). Syncytin- 1 mediates… 
Highly Cited
2013
Highly Cited
2013
Expression of Human Endogenous Retrovirus-W Including Syncytin-1 in Cutaneous T-Cell Lymphoma
The pathomechanism of mycosis fungoides (MF), the most common type of primary cutaneous T-cell lymphomas (CTCLs) and a malignancy… 
2012
2012
High-Temperature Requirement Protein A4 (HtrA4) Suppresses the Fusogenic Activity of Syncytin-1 and Promotes Trophoblast Invasion
ABSTRACT Cell-cell fusion and cell invasion are essential for placental development. Human cytotrophoblasts in the chorionic… 
Highly Cited
2011
Highly Cited
2011
Involvement of human endogenous retroviral syncytin-1 in human osteoclast fusion.
Highly Cited
2009
Highly Cited
2009
Comparative Methylation of ERVWE1/Syncytin-1 and Other Human Endogenous Retrovirus LTRs in Placenta Tissues
Human endogenous retroviruses (HERVs) are globally silent in somatic cells. However, some HERVs display high transcription in… 
Highly Cited
2007
Highly Cited
2007
The Human Endogenous Retrovirus Envelope Glycoprotein, Syncytin-1, Regulates Neuroinflammation and Its Receptor Expression in Multiple Sclerosis: A Role for Endoplasmic Reticulum Chaperones in…
Retroviral envelopes are pathogenic glycoproteins which cause neuroinflammation, neurodegeneration, and endoplasmic reticulum… 
Highly Cited
2006
Highly Cited
2006
Proliferation and cell–cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin-1 and regulated by TGF-β
Endometrial carcinomas (EnCa) predominantly represent a steroid hormone-driven tumor initiated from prestages. The human… 
2006
2006
Fusiogenic endogenous-retroviral syncytin-1 exerts anti-apoptotic functions in staurosporine-challenged CHO cells
Fusiogenic glycoprotein syncytin-1, expressed in human placenta, is a promising candidate for acquiring a basic knowledge of… 
2006
2006
C-Terminal truncations of syncytin-1 (ERVWE1 envelope) that increase its fusogenicity
Abstract Syncytin-1, the envelope protein of ERVWE1, an endogenous retrovirus of the HERV-W family, plays an important role in… 
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