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sulopenem
A parenteral thiopenem with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. Sulopenem is not active…
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National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (2)
CP 70429
PF-03709270
Broader (1)
Lactams
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
1393. A Phase 1, Randomized, Open-Label, Crossover Study in Healthy Subjects Under Fasting Conditions of Orally Administered Sulopenem Etzadroxil Alone or with Probenecid to Determine the…
M. Dunne
,
S. Aronin
,
E. Dunzo
,
S. Puttagunta
Open Forum Infectious Diseases
2018
Corpus ID: 53858424
Abstract Background Antimicrobial resistance to available oral antibiotics is becoming progressively more common, precipitating…
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2009
2009
Comparative Antipneumococcal Activities of Sulopenem and Other Drugs
K. Kosowska-Shick
,
L. Ednie
,
P. Mcghee
,
P. Appelbaum
Antimicrobial Agents and Chemotherapy
2009
Corpus ID: 46131908
ABSTRACT For 297 penicillin-susceptible, -intermediate, and -resistant pneumococcal strains, the sulopenem MIC50s were 0.008, 0…
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2008
2008
Reduction of in-source collision-induced dissociation and thermolysis of sulopenem prodrugs for quantitative liquid chromatography/electrospray ionization mass spectrometric analysis by promoting…
C. E. Wujcik
,
E. Kadar
Rapid Communications in Mass Spectrometry
2008
Corpus ID: 38911732
Six chromatographically resolved sulopenem prodrugs were monitored for their potential to undergo both in-source collision…
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2008
2008
In Vitro Antibacterial Activity of Sulopenem: A New Oral Penem Antimicrobial Versus Recent Bacterial Clinical Isolates
M. Huband
2008
Corpus ID: 87029358
2008
2008
In Vivo Efficacy of Novel Prodrugs of Sulopenem
L. Lamb
2008
Corpus ID: 112335117
2008
2008
Anti-Anaerobic Activity of Sulopenem Compared to Other Agents
L. Ednie
2008
Corpus ID: 86886543
2003
2003
Biopharmaceutical-Based Pharmacokinetic Modeling of Sulopenem Prodrugs: Impact of Luminal Stability on Fraction of Dose Absorbed
J. O’Donnell
,
K. Brighty
,
+12 authors
J. Winton
2003
Corpus ID: 62376765
1996
1996
[In vitro and in vivo activities of sulopenem compared with those of imipenem and cephalosporins].
M. Nagashima
,
S. Goto
,
T. Yoshida
,
T. Matsunaga
,
H. Shimohira
,
M. Ogawa
The Japanese Journal of Antibiotics
1996
Corpus ID: 32063833
The in vitro and in vivo antibacterial activities of sulopenem (CP-70,429),a new parenteral penem antibiotic, were compared with…
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1996
1996
[In vitro antibacterial activity of a new parenteral penem, sulopenem].
T. Yoshida
,
E. Tateda
,
K. Hiramatsu
,
T. Yokota
The Japanese Journal of Antibiotics
1996
Corpus ID: 36741140
Eighty percent minimum inhibitory concentrations (MIC80) of sulopenem against clinically isolated 12 to 80 strains of each of…
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1996
1996
Sulopenem 抗菌活性の基礎的, 細菌学的検討
T. Yoshida
,
E. Tateda
,
K. Hiramatsu
,
Takeshi Yokota
1996
Corpus ID: 83382629
Eighty percent minimum inhibitory concentrations (MIC80) of sulopenem against clinically isolated 12 to 80 strains of each of…
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