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sulopenem

A parenteral thiopenem with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. Sulopenem is not active… 
National Institutes of Health

Papers overview

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2019
2019
ABSTRACT Urinary tract infections (UTIs) caused by antibiotic-resistant Gram-negative bacteria are a growing concern due to… 
2018
2018
The in vitro activity of sulopenem was assessed against a collection from 2014 to 2016 of 539 urinary isolates of Escherichia… 
Highly Cited
2015
Highly Cited
2015
This Account describes the use of molecular dynamics (MD) simulations to reveal how mutations alter the structure and… 
Highly Cited
2015
Highly Cited
2015
Significance Ketoreductases are the most commonly used enzymes in industrial pharmaceutical synthesis. We investigated the nature… 
Review
2012
Review
2012
Natural and man-made organosulfur compounds play important roles in biological and medicinal chemistry. Among the various classes… 
2009
2009
ABSTRACT Agar dilution MIC methodology was used to compare the activity of sulopenem with those of amoxicillin/clavulanate… 
Highly Cited
2006
Highly Cited
2006
ABSTRACT Clinical isolates of Klebsiella pneumoniae resistant to carbapenems and essentially all other antibiotics (multidrug… 
Highly Cited
2005
Highly Cited
2005
ABSTRACT Acinetobacter spp. are emerging as opportunistic hospital pathogens that demonstrate resistance to many classes of… 
Review
2003
Review
2003
Many β‐lactam antimicrobials were developed between the 1960s and 1980s, with continuing development driven by the emergence of… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT Pseudomonas aeruginosa exhibits high intrinsic resistance to penem antibiotics such as faropenem, ritipenem, AMA3176…