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sulfinosine

Known as: 2-amino-9-beta--ribofuranosylpurine-6-sulfinamide, 9H-Purine-6-sulfinamide, 2-amino-9-beta-D-ribofuranosyl- 
National Institutes of Health

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Purine Nucleosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Purine Nucleoside Analog - Sulfinosine Modulates Diverse Mechanisms of Cancer Progression in Multi-Drug Resistant Cancer Cell Lines
Achieving an effective treatment of cancer is difficult, particularly when resistance to conventional chemotherapy is developed… 
2009
2009
Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R)
SummaryA resistant non-small cell lung carcinoma cell line—NSCLC (NCI-H460/R) was established in order to investigate the… 
2008
2008
Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)
Multidrug resistance (MDR) is the main obstacle to a successful chemotherapy of lung cancer. We tested the potential of… 
2006
2006
The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro
SummaryTo identify purine analogs that could be effective in treating neuroblastomas, we tested the anticancer properties of… 
2002
2002
Sulfinosine-Induced Cell Growth Inhibition and Apoptosis in Human Lung Carcinomas In Vitro
In spite of tremendous effort for improvedtherapy, lung cancer remains the leadingcause of cancer-related deaths worldwide.In the… 
1994
1994
Sulfinosine congeners: synthesis and antitumor activity in mice of certain N9-alkylpurines and purine ribonucleosides.
A number of N9-alkyl-substituted purines and purine ribonucleosides have been synthesized as congeners of sulfinosine and… 
1991
1991
Analysis of the in vitro antitumor activity of novel purine-6-sulfenamide, -sulfinamide, and -sulfonamide nucleosides and certain related compounds using a computer-aided receptor modeling procedure.
The comparative antileukemic activities of 21 novel nucleosides were determined in vitro by using cultured L1210 cells and… 
1990
1990
Chemotherapeutic characterization in mice of 2-amino-9-beta-D-ribofuranosylpurine-6-sulfinamide (sulfinosine), a novel purine nucleoside with unique antitumor properties.
In preclinical investigations performed in mice, 2-amino-9-beta-D-ribofuranosyl purine-6-sulfinamide (sulfinosine), a novel… 
1990
1990
Synthesis and antitumor evaluation in mice of certain 7-deazapurine (pyrrolo[2,3-d]pyrimidine) and 3-deazapurine (imidazo[4,5-c]pyridine) nucleosides structurally related to sulfenosine, sulfinosine…
7-Deaza (pyrrolo[2,3-d]pyrimidine) and 3-deaza (imidazo[4,5-c]pyridine) congeners of sulfenosine (5a and 9), sulfinosine (6a and… 
1990
1990
Synthesis and in vivo antitumor activity of 2-amino-9H-purine-6-sulfenamide, -sulfinamide, and -sulfonamide and related purine ribonucleosides.
A number of 6-sulfenamide, 6-sulfinamide, and 6-sulfonamide derivatives of 2-aminopurine and certain related purine… 
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