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sulfinosine

Known as: 2-amino-9-beta--ribofuranosylpurine-6-sulfinamide, 9H-Purine-6-sulfinamide, 2-amino-9-beta-D-ribofuranosyl- 
National Institutes of Health

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Purine Nucleosides

Papers overview

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2010
2010
Purine analogs sensitize the multidrug resistant cell line (NCI-H460/R) to doxorubicin and stimulate the cell growth inhibitory effect of verapamil
SummaryThe resistant cell line NCI-H460/R and its counterpart NCI-H460 were used to investigate the ability of purine analogs to… 
2009
2009
Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R)
SummaryA resistant non-small cell lung carcinoma cell line—NSCLC (NCI-H460/R) was established in order to investigate the… 
2008
2008
Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)
Multidrug resistance (MDR) is the main obstacle to a successful chemotherapy of lung cancer. We tested the potential of… 
2007
2007
353 POSTER Effect of sulfinosine [(R, S)-2-amino-9-beta-D-ribofuranosylpurine-6-sulfinamide] on lung carcinoma cell lines and its role in overcoming multidrug resistance
2006
2006
The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro
SummaryTo identify purine analogs that could be effective in treating neuroblastomas, we tested the anticancer properties of… 
2002
2002
Sulfinosine-Induced Cell Growth Inhibition and Apoptosis in Human Lung Carcinomas In Vitro
In spite of tremendous effort for improvedtherapy, lung cancer remains the leadingcause of cancer-related deaths worldwide.In the… 
1990
1990
Synthesis and antitumor evaluation in mice of certain 7-deazapurine (pyrrolo[2,3-d]pyrimidine) and 3-deazapurine (imidazo[4,5-c]pyridine) nucleosides structurally related to sulfenosine, sulfinosine…
7-Deaza (pyrrolo[2,3-d]pyrimidine) and 3-deaza (imidazo[4,5-c]pyridine) congeners of sulfenosine (5a and 9), sulfinosine (6a and… 
1990
1990
Chemotherapeutic characterization in mice of 2-amino-9-beta-D-ribofuranosylpurine-6-sulfinamide (sulfinosine), a novel purine nucleoside with unique antitumor properties.
In preclinical investigations performed in mice, 2-amino-9-beta-D-ribofuranosyl purine-6-sulfinamide (sulfinosine), a novel… 
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