sterol metabolic process

Known as: sterol metabolism 
The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule. [ISBN… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
05101519562016

Papers overview

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Highly Cited
2008
Highly Cited
2008
LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response
Cholesterol is essential for membrane synthesis; however, the mechanisms that link cellular lipid metabolism to proliferation are… (More)
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2007
2007
Networks from drug–drug surfaces
Multi-drug combinations are vital in modern medicine (Keith et al, 2005; Fitzgerald et al, 2006). Such drug combinations can also… (More)
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Highly Cited
2006
Highly Cited
2006
Abnormalities of cholesterol metabolism in autism spectrum disorders.
Although Smith-Lemli-Opitz Syndrome (SLOS), a genetic condition of impaired cholesterol biosynthesis, is associated with autism… (More)
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Highly Cited
2005
Highly Cited
2005
High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial.
BACKGROUND Myopathy, probably caused by 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibition in skeletal muscle, rarely… (More)
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Highly Cited
2005
Highly Cited
2005
Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia.
Typically, autosomal dominant familial hypercholesterolaemia (FH) is caused by mutations in the low density lipoprotein (LDL… (More)
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2001
2001
ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism.
BACKGROUND AND AIMS Members of the family of ABC transporters are involved in different processes of sterol metabolism, and ABCA1… (More)
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2000
2000
Serum, biliary, and fecal cholesterol and plant sterols in colectomized patients before and during consumption of stanol ester margarine.
BACKGROUND Cholesterol metabolic studies are simplified in colectomized patients because of rapid intestinal passage and reduced… (More)
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2000
2000
Cholesterol absorption efficiency and sterol metabolism in obesity.
Role of enterohepatic cholesterol metabolism in obesity-induced increase of cholesterol synthesis was studied in healthy lean… (More)
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Highly Cited
1996
Highly Cited
1996
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.
Past experiments and current paradigms of cholesterol homeostasis suggest that cholesterol 7alpha-hydroxylase plays a crucial… (More)
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Highly Cited
1993
Highly Cited
1993
Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism.
Organelles of the yeast Saccharomyces cerevisiae were isolated and analyzed for sterol composition and the activity of three… (More)
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