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National Institutes of Health
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T-18, a stemonamide synthetic intermediate inhibits Pim kinase activity and induces cell apoptosis, acting as a potent anticancer drug.
Corpus ID: 6483221
Pim-3 kinase has been shown to be aberrantly expressed in premalignant and malignant lesions of endoderm-derived…
Total synthesis of (±)-maistemonine and (±)-stemonamide.
Corpus ID: 23689735
The first total synthesis of polycyclic Stemona alkaloid maistemonine has been achieved. The efficient approach features a…
Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis‐inducing ability
International journal of cancer
Corpus ID: 24925762
We previously demonstrated that Pim‐3, a protooncogene with serine/threonine kinase activity, was aberrantly expressed in…
Total synthesis of (+/-)-stemonamide and (+/-)-isostemonamide using a radical cascade.
Corpus ID: 39853522
Total synthesis of stemonamide and isostemonamide is described. The concise construction of the tricyclic core of these alkaloids…
First total synthesis of (+/-)-stemonamide and (+/-)-isostemonamide.
J. I. Hernando
Corpus ID: 23235584
[structure: see text] The total synthesis of the tetracyclic alkaloids stemonamide (1) and isostemonamide (2) is presented. The…
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