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Mangiferin suppresses CIA by suppressing the expression of TNF-α, IL-6, IL-1β, and RANKL through inhibiting the activation of NF-κB and ERK1/2.
- M. Tsubaki, T. Takeda, S. Nishida
- Biology, MedicineAmerican journal of translational research
- 15 August 2015
Mangiferin suppressed the progression and incidence of CIA in DBA1/J mice and markedly inhibited not only developing but also clinically evident CIA, suggesting that mangiferin has potential clinical applications for the treatment of rheumatoid arthritis.
Salacinol, potent antidiabetic principle with unique thiosugar sulfonium sulfate structure from the Ayurvedic traditional medicine Salacia reticulata in Sri Lanka and India
Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.
Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens[S]
Using RNA-Seq technology, a cortisol-inducible (∼1,000-fold) operon (desABCD) encoding at least one enzyme involved in anaerobic side-chain cleavage is identified andylogenetic analysis suggests this operon is rare in nature and the desC gene evolved from a gene encoding threonine dehydrogenase.
Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potent α-glucosidase inhibitors.
Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity
A quantitative analytical method for five aporphine alkaloids, nuciferine (1), nornuciferine (2), N-methylasimilobine (3), asimilobine (4), and pronuciferine (5), and five benzylisoquinoline…
Synthesis and elucidation of absolute stereochemistry of salaprinol, another thiosugar sulfonium sulfate from the ayurvedic traditional medicine Salacia prinoides
Salaprinol and Ponkoranol with Thiosugar Sulfonium Sulfate Structure from Salacia prinoides and α-Glucosidase Inhibitory Activity of Ponkoranol and Kotalanol Desulfate.
Synthesis and Elucidation of Absolute Stereochemistry of Salaprinol, Another Thiosugar Sulfonium Sulfate from the Ayurvedic Traditional Medicine Salacia prinoides.
Absolute stereostructure of potent alpha-glucosidase inhibitor, Salacinol, with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata.