Mangiferin suppresses CIA by suppressing the expression of TNF-α, IL-6, IL-1β, and RANKL through inhibiting the activation of NF-κB and ERK1/2.
- M. Tsubaki, T. Takeda, S. Nishida
- Biology, MedicineAmerican journal of translational research
- 15 August 2015
Mangiferin suppressed the progression and incidence of CIA in DBA1/J mice and markedly inhibited not only developing but also clinically evident CIA, suggesting that mangiferin has potential clinical applications for the treatment of rheumatoid arthritis.
Salacinol, potent antidiabetic principle with unique thiosugar sulfonium sulfate structure from the Ayurvedic traditional medicine Salacia reticulata in Sri Lanka and India
- M. Yoshikawa, T. Murakami, O. Muraoka
- Chemistry
- 1 December 1997
Inhibitors of nitric oxide production from the rhizomes of Alpinia galanga: structures of new 8-9' linked neolignans and sesquineolignan.
- T. Morikawa, S. Ando, H. Matsuda, Shin-ya Kataoka, O. Muraoka, M. Yoshikawa
- ChemistryChemical and pharmaceutical bulletin
- 1 June 2005
The 80% aqueous acetone extract from the rhizomes of Alpinia galanga showed nitric oxide production inhibitory activities in mouse peritoneal macrophages, and three new 8-9' linked neolignans, galanganal, galangols A and B, and a sesquineolignan, Galanganol C, were isolated together with nine known phenylpropanoids and p-hydroxybenzaldehyde.
Alkaloid constituents from flower buds and leaves of sacred lotus (Nelumbo nucifera, Nymphaeaceae) with melanogenesis inhibitory activity in B16 melanoma cells.
- Seikou Nakamura, Souichi Nakashima, M. Yoshikawa
- Chemistry, BiologyBioorganic & Medicinal Chemistry
- 1 February 2013
Phenylethanoid oligoglycosides and acylated oligosugars with vasorelaxant activity from Cistanche tubulosa.
- M. Yoshikawa, H. Matsuda, T. Morikawa, Haihui Xie, Seikou Nakamura, O. Muraoka
- ChemistryBioorganic & Medicinal Chemistry
- 15 November 2006
Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa.
- T. Morikawa, Yingni Pan, O. Muraoka
- Chemistry, BiologyBioorganic & Medicinal Chemistry
- 1 March 2010
Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potent α-glucosidase inhibitors.
- Weijia Xie, G. Tanabe, O. Muraoka
- ChemistryBioorganic & Medicinal Chemistry
- 15 March 2011
Megastigmanes and their glucosides from the whole plant of Sedum sarmentosum.
- M. Yoshikawa, T. Morikawa, Yi Zhang, Seikou Nakamura, O. Muraoka, H. Matsuda
- ChemistryJournal of Natural Products
- 10 February 2007
The absolute stereostructures of 1-8 were elucidated on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.
Perennisosides I-VII, acylated triterpene saponins with antihyperlipidemic activities from the flowers of Bellis perennis.
- T. Morikawa, Xuezheng Li, M. Yoshikawa
- ChemistryJournal of Natural Products
- 26 March 2008
The methanolic extract and its saponin fraction (methanol-eluted fraction) of the flowers of Bellis perennis were found to suppress serum triglyceride elevation in olive oil-treated mice. From the…
Quantitative determination of potent alpha-glucosidase inhibitors, salacinol and kotalanol, in Salacia species using liquid chromatography-mass spectrometry.
- O. Muraoka, T. Morikawa, Sohachiro Miyake, Junji Akaki, K. Ninomiya, M. Yoshikawa
- ChemistryJournal of Pharmaceutical and Biomedical Analysis
- 5 September 2010
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