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src Oncogene

Known as: v-src Oncogenes, Oncogene SRC, Gene, v-src 
A retroviral DNA or mutated host gene that encodes a hyperactive form of the proto-oncogene tyrosine-protein kinase Src protein. This oncogene is… 
National Institutes of Health

Related topics

Related topics

8 relations
20q12-q13Homo sapiensNeoplastic Cell TransformationProtein phosphorylation

Broader (1)

Genes, src

Papers overview

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2011
2011
Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness
Crk-associated substrate (CAS) Tyr-12 phosphorylation has an important role in ligand binding, CAS localization, turnover of… 
Highly Cited
1997
Highly Cited
1997
Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs
The v-src oncogene encodes a nonreceptor tyrosine kinase. When this gene was expressed in the myeloblastic cell line 32Dcl3, it… 
Highly Cited
1995
Highly Cited
1995
Isolation and characterization of a novel mitogenic regulatory gene, 322, which is transcriptionally suppressed in cells transformed by src and ras
In an attempt to isolate novel regulatory and/or tumor suppressor genes, we identified cDNAs whose abundance is low in NIH 3T3… 
1992
1992
Phosphorylation of connexin43 in cells containing mutant src oncogenes.
Disruption of gap junctional communication (measured by intercellular dye transfer) in cultured fibroblasts by pp60v-src is… 
Review
1988
Review
1988
Expression of proto-oncogenes in neural tissues
1987
1987
Effect of infection with murine recombinant retroviruses containing the v-src oncogene on interleukin 2- and interleukin 3-dependent growth states.
The cloned murine interleukin 3 (IL 3)-dependent cell lines FD.C/1, 32Dc1-23, and KP3 can each be switched to interleukin 2 (IL 2… 
Highly Cited
1986
Highly Cited
1986
Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes
In vitro infection of bone marrow or fetal liver cells with retroviruses containing fes, abl, ras, or src oncogenes resulted in… 
1986
1986
Activation of the cellular src gene by transducing retrovirus
Newly isolated strains of avian sarcoma virus, S1 and S2, were shown to have the transduced cellular src gene as their viral… 
1985
1985
Rous sarcoma virus variants that encode src proteins with an altered carboxy terminus are defective for cellular transformation
The src gene of Rous sarcoma virus (v-src) and its cellular homolog, the c-src gene, share extensive sequence homology. The most… 
1976
1976
Distribution of envelope-specific and sarcoma-specific nucleotide sequences from different parents in the RNAs of avian tumor virus recombinants.
The distribution of leukosis-virus- and sarcoma-virus-specific oligonucleotide sequences was investigated in the RNAs of viral… 
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