spindle midzone

Known as: central spindle, spindle equator 
The area in the center of the spindle where the spindle microtubules from opposite poles overlap. [GOC:ai, PMID:15296749]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2017
0204019622017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Proper partitioning of the contents of a cell between two daughters requires integration of spatial and temporal cues. The… (More)
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Highly Cited
2004
Highly Cited
2004
A number of proteins accumulate in the anaphase spindle midzone, but the interaction and precise role of these proteins in… (More)
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Highly Cited
2004
Highly Cited
2004
The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the… (More)
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Highly Cited
2002
Highly Cited
2002
Midzone microtubules of mammalian cells play an essential role in the induction of cell cleavage, serving as a platform for a… (More)
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Highly Cited
2001
Highly Cited
2001
Aurora/Ipl1-related kinases are a conserved family of enzymes that have multiple functions during mitotic progression. Although… (More)
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Highly Cited
2001
Highly Cited
2001
Cell divisions that create daughter cells of different sizes are crucial for the generation of cell diversity during animal… (More)
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Highly Cited
2000
Highly Cited
2000
Baculoviral IAP repeat proteins (BIRPs) may affect cell death, cell division, and tumorigenesis. The C. elegans BIRP BIR-1 was… (More)
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Highly Cited
2000
Highly Cited
2000
During cytokinesis of animal cells, the mitotic spindle plays at least two roles. Initially, the spindle positions the… (More)
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Highly Cited
1999
Highly Cited
1999
Previous genetic and biochemical studies have led to the hypothesis that the essential mitotic bipolar kinesin, KLP61F, cross… (More)
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Highly Cited
1998
Highly Cited
1998
Members of the MKLP1 subfamily of kinesin motor proteins localize to the equatorial region of the spindle midzone and are capable… (More)
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