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  • S. Yang, A. Burgin, B. N. Huizenga, C. Robertson, K. Yao, H. Nash
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1996 (First Publication: 15 October 1996)
  • The covalent joining of topoisomerases to DNA is normally a transient step in the reaction cycle of these important enzymes. However, under a variety of circumstances, the covalent complex isExpand
  • Kariamanikkam Srinivasa Krishnan, Howard A. Nash
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 1990 (First Publication: 1 November 1990)
  • In an attempt to identify genes that control or encode the targets of general anesthetics, we have chemically mutagenized fruit flies and selected four lines that show an abnormal response to theExpand