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sphingolipid catabolic process

Known as: sphingolipid breakdown, sphingolipid catabolism, sphingolipid degradation 
The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2017
024619702017

Papers overview

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2017
2017
Stress-Activated Degradation of Sphingolipids Regulates Mitochondrial Function and Cell Death in Yeast
Sphingolipids are regulators of mitochondria-mediated cell death in higher eukaryotes. Here, we investigate how changes in… (More)
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Review
2016
Review
2016
Neuronal sphingolipidoses: Membrane lipids and sphingolipid activator proteins regulate lysosomal sphingolipid catabolism.
Glycosphingolipids and sphingolipids of cellular plasma membranes (PMs) reach luminal intra-lysosomal vesicles (LVs) for… (More)
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2012
2012
Sphingolipid Degradation in Leishmania (Leishmania) amazonensis
BACKGROUND Human leishmaniasis is caused by more than 20 Leishmania species and has a wide range of symptoms. Our recent studies… (More)
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2011
2011
The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner.
The bioactive signaling molecule D-erythro-sphingosine-1-phosphate (S1P) is irreversibly degraded by the enzyme S1P lyase (SPL… (More)
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2007
2007
Arsenic trioxide induces accumulation of cytotoxic levels of ceramide in acute promyelocytic leukemia and adult T-cell leukemia/lymphoma cells through de novo ceramide synthesis and inhibition of…
BACKGROUND AND OBJECTIVES Arsenic trioxide (ATO) is an effective treatment for acute promyelocytic leukemia (APL) and potentially… (More)
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2003
Review
2003
Die pigmentierte Form der orthochromatischen Leukodystrophie
Die pigmentierte Form der orthochromatischen Leukodystrophie (M. van Bogaert-Nyssen) ist eine wenig bekannte neurologische… (More)
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2001
2001
1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate.
Owing to its ability to induce growth arrest and differentiation of keratinocytes, 1alpha,25-dihydroxyvitamin D3 and its analogs… (More)
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2001
2001
Sphingolipid metabolic changes during chiral C2-ceramides induced apoptosis in human leukemia cells.
N-acetylsphingosine (C2-ceramide) is a synthetic water-soluble ceramide mimicking the activity of natural ceramides. By fixing… (More)
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1998
1998
Analysis of bax protein in sphingosine-induced apoptosis in the human leukemic cell line TF1 and its bcl-2 transfectants.
Sphingosine, a sphingolipid breakdown product, has been proposed as an apoptosis-inducing agent. In this study, we examined the… (More)
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Review
1970
Review
1970
Enzymatic aspects of sphingolipid degradation.
 
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