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solute carrier family 11- (proton-coupled divalent metal ion transporters), member 2

Known as: SLC11A2 protein, DCT1 transporter, divalent metal transporter-1 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Cation Transport Proteins

Narrower (1)

DMT-1 transporter, zebrafish
SLC11A2 gene

Papers overview

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Highly Cited
2011
Highly Cited
2011
T‐type calcium channel as a portal of iron uptake into cardiomyocytes of beta‐thalassemic mice
Objectives: Iron‐overload condition can be found in β‐thalassemic patients with regular blood transfusion, leading to iron… 
Highly Cited
2007
Highly Cited
2007
Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1
Hereditary hemochromatosis and transfusional iron overload are frequent clinical conditions associated with progressive iron… 
Highly Cited
2006
Highly Cited
2006
A manganese-enhanced diet alters brain metals and transporters in the developing rat.
Manganese (Mn) neurotoxicity in adults can result in psychological and neurological disturbances similar to Parkinson's disease… 
2005
2005
Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis
Although the recent identification of several genes has extended our knowledge on the maintenance of body iron homeostasis, their… 
Review
2004
Review
2004
New evidence of iron and zinc interplay at the enterocyte and neural tissues.
Because combined iron-zinc supplementation regimens are employed with increasing frequency in field trials to combat co-occurring… 
Highly Cited
2004
Highly Cited
2004
Distribution of divalent metal transporter-1 in the monkey basal ganglia
Highly Cited
2002
Highly Cited
2002
Iron increases expression of iron-export protein MTP1 in lung cells.
Accumulation of reactive iron in acute and chronic lung disease suggests that iron-driven free radical formation could contribute… 
Highly Cited
2002
Highly Cited
2002
Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells.
The capacity of natural resistance-associated macrophage protein-2 [Nramp2; also called divalent metal transporter-1 (DMT1) and… 
Highly Cited
2002
Highly Cited
2002
Copper repletion enhances apical iron uptake and transepithelial iron transport by Caco-2 cells.
The influence of copper status on Caco-2 cell apical iron uptake and transepithelial transport was examined. Cells grown for 7-8… 
Highly Cited
2000
Highly Cited
2000
Identification and localization of divalent metal transporter-1 (DMT-1) in term human placenta.
The mechanism by which iron is transported from mother to fetus is incompletely understood. Whereas transferrin receptor (TfR) is… 
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