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sn-1,2-Didecanoylglycerol

Known as: Decanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester, (S)-, DiC10 
A synthetic lipid second messenger. As an analog of the second messenger diacylglycerol, sn-1,2-didecanoylglycerol substitutes for diacylglycerol in… 
National Institutes of Health

Papers overview

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1996
1996
Phosphatidic acid binding to human neutrophils: effects on tyrosine kinase-regulated intracellular Ca2+ mobilization.
1992
1992
Diacylglycerol inhibits potassium-induced calcium influx and insulin release by a protein kinase-C-independent mechanism in HIT T-15 islet cells.
We reported previously that in pancreatic islet cells, certain diacylglycerols (DGs) evoke increases in cytosolic calcium ([Ca2… 
1990
1990
Altered O2-/H2O2 production ratio by in vitro and in vivo primed human neutrophils.
1989
1989
Synthetic lipid second messenger sn-1,2-didecanoylglycerol: a complete tumor promoter in mouse skin.
sn-1,2-Didecanoylglycerol, a synthetic lipid second messenger and model diacylglycerol, was evaluated as a complete skin tumor… 
1989
1989
Effects of bryostatins and retinoic acid on phorbol ester- and diacylglycerol-induced squamous differentiation in human tracheobronchial epithelial cells.
Previous studies have shown that normal human tracheobronchial epithelial (HBE) cells undergo squamous differentiation upon… 
1988
1988
Comparison of the effect of sn-1,2-didecanoylglycerol and 12-O-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD-1 mice.
Since sn-1,2-didecanoylglycerol mimics 12-O-tetradecanoylphorbol-13-acetate (TPA) by inducing ornithine decarboxylase activity… 
1988
1988
sn-1,2-didecanoylglycerol effectively induces epidermal ornithine decarboxylase but only weak hyperplasia in mouse skin.
The abilities of sn-1,2-didecanoylglycerol (sn-1,2-DDG) to induce epidermal ornithine decarboxylase (ODC) activity and epidermal… 
1986
1986
Incorporation of synthetic 1,2‐diacylglycerol into platelet phosphatidylinositol is increased by cyclic AMP
Highly Cited
1986
Highly Cited
1986
Transmembrane signals mediating neural peptide secretion: role of protein kinase C activators and arachidonic acid metabolites in luteinizing hormone-releasing hormone secretion.
The present experiments were designed to determine the effects of different activators of protein kinase C on the secretion of… 
1985
1985
Diacylglycerol and phorbol esters enhance LHRH and prostaglandin E2 secretion from median eminence nerve terminals in vitro
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