sinefungin

Known as: Adenosyl-Ornithine, (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid, adenosylornithine 
A natural nucleoside related to S-adenosylmethionine that has been isolated from Streptomyces species with antifungal, antiviral and antiparasitic… (More)

Topic mentions per year

Topic mentions per year

1978-2017
051019782017

Papers overview

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2012
2012
Epigenetic regulation is involved in numerous physiological and pathogenic processes. Among the key regulators that orchestrate… (More)
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2011
2011
The type IIS/IIC restriction endonuclease TspGWI recognizes the sequence 5'-ACGGA-3', cleaving DNA 11/9 nucleotides downstream… (More)
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Highly Cited
2009
Highly Cited
2009
DNA methylation, histone modifications, and nucleosomal occupancy collaborate to cause silencing of tumor-related genes in cancer… (More)
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1999
1999
Complete parasite development was obtained in differentiated human enterocytic HCT-8 cells infected at confluence with… (More)
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1997
1997
The crystal structures of the binary complexes of the DNA methyltransferase M.TaqI with the inhibitor Sinefungin and the reaction… (More)
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1996
1996
Sinefungin is an antibiotic possessing a strong anti-leishmanial activity. Among the most important effects of this molecule on… (More)
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1993
1993
Promastigotes resistant to sinefungin (SF), a nucleoside antibiotic that is structurally related to S-adenosylmethionine (AdoMet… (More)
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1984
1984
The antifungal antibiotic sinefungin, a potent inhibitor of methyl transferases and a potential inhibitor of polyamine… (More)
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1983
1983
Sinefungin, a naturally occurring antifungal antibiotic nucleoside containing an ornithine residue, linked by a C-C bond to C-5… (More)
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1978
1978
Sinefungin (A9145) and a related metabolite, A9145C, were found to be potent inhibitors of Newcastle disease virion and vaccinia… (More)
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