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simmitecan

Known as: 9-allyl-10-piperidyl piperidine formyloxy-camptothecin 
National Institutes of Health

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2 relations

Broader (1)

Camptothecin
analogs & derivatives

Papers overview

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2020
2020
A phase Ib study of simmitecan (LP) single-agent and in combination with 5-fluorouracil/leucovorin (5-FU/LV) or thalidomide (T) in patients with advanced solid tumor.
3523Background: Simmitecan (LP), a novel 9-substituted lipophilic camptothecin derivative, is a potent inhibitor of topoisomerase… 
2011
2011
Accurate determination of the anticancer prodrug simmitecan and its active metabolite chimmitecan in various plasma samples based on immediate deactivation of blood carboxylesterases.
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