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Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis
The metastatic organotropism has been one of the cancer's greatest mysteries since the ‘seed and soil' hypothesis. Although the role of EGFR in cancer cells is well studied, the effects of secretedExpand
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Exosomal circRNA derived from gastric tumor promotes white adipose browning by targeting the miR‐133/PRDM16 pathway
Cancer‐related cachexia is a metabolic syndrome characterized by a wasting disorder of adipose and skeletal muscle and is accompanied by body weight loss and systemic inflammation. The treatmentExpand
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Exosomal miR-27a Derived from Gastric Cancer Cells Regulates the Transformation of Fibroblasts into Cancer-Associated Fibroblasts
Background/Aims: The malignant biological behavior of gastric cancer(GC) is not only determined by cancer cells alone, but also closely regulated by the microenvironment. Fibroblasts represent aExpand
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Clinical outcome of 31 patients with primary malignant melanoma of the vagina
Objective To investigate the clinical characteristics of and prognostic factors for primary malignant melanoma of the vagina. Methods Clinical data from 31 patients treated for primary malignantExpand
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Rolling circle amplification combined with gold nanoparticle aggregates for highly sensitive identification of single-nucleotide polymorphisms.
A highly sensitive and specific colorimetry-based rolling circle amplification (RCA) assay method for single-nucleotide polymorphism genotyping has been developed. A circular template is generated byExpand
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Genome-wide cloning, identification, classification and functional analysis of cotton heat shock transcription factors in cotton (Gossypium hirsutum)
BackgroundHeat shock transcriptional factors (Hsfs) play important roles in the processes of biotic and abiotic stresses as well as in plant development. Cotton (Gossypium hirsutum, 2n = 4x = (AD)2 =Expand
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Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer.
  • Xinyi Wang, H. Zhang, +7 authors Y. Ba
  • Chemistry, Medicine
  • Molecular therapy : the journal of the American…
  • 7 March 2018
Chemoresistance is one of the causes of adverse effects in gastric cancer, including a poor response to cisplatin (DDP). Exosomes loaded with microRNA (miRNA), mRNA, and other non-coding RNAs couldExpand
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An electrochemical impedance immunosensor with signal amplification based on Au-colloid labeled antibody complex
Abstract A highly sensitive electrochemical impedance immunosensor was developed by using a novel amplification procedure with the application of a Au-colloid labeled antibody as the primaryExpand
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Serum miRNA expression profile as a prognostic biomarker of stage II/III colorectal adenocarcinoma
We sought to identify a serum miRNA expression profile to improve disease surveillance and to predict post-operative disease recurrence for stage II/III colorectal cancer (CRC) patients. Using theExpand
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Onco-miR-130 promotes cell proliferation and migration by targeting TGFβR2 in gastric cancer
MicroRNAs (miRNAs) have been proved to play crucial roles in tumorigenesis. TGFβ signal pathway abnormality is found in various cancers and correlates with tumor proliferation and metastasis.Expand
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