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sigma-1 receptor

Known as: receptor 1, sigma, sigma-1 receptors 
National Institutes of Health

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1 relation

Broader (1)

Receptors, sigma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Effects of the Dopamine Stabilizer, Pridopidine, on Basal and Phencyclidine-Induced Locomotion: Role of Dopamine D2 and Sigma-1 Receptors.
BACKGROUND Pridopidine, a compound in clinical trials for Huntington's disease treatment, was originally synthesized as a… 
2017
2017
APEX2-enhanced electron microscopy distinguishes sigma-1 receptor localization in the nucleoplasmic reticulum
The sigma-1 receptor (Sig1R) is an endoplasmic reticulum chaperonin that is attracting tremendous interest as a potential anti… 
2017
2017
Abstract 2900: Sigma-1 receptor control tumorigenic and stem cell-like phenotype in human cancers
Tumor-initiating stem-like cancer cells drive tumor progression, metastasis and treatment failure. Understanding the pathways… 
2016
2016
Sigma-1 Receptor as a Pluripotent Modulator in the Living System
The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum (ER) protein resides specifically at the interface between ER and… 
2016
2016
A systematic exploration of the effects of flexibility and basicity on sigma (σ) receptor binding in a series of substituted diamines.
The sigma-1 receptor (S1R) has attracted a great deal of attention as a prospective drug target due to its involvement in… 
Review
2014
Review
2014
Effect of the Sigma-1 receptor on neurite outgrowth
Neurite outgrowth is one of the essential processes underlying development and plasticity of the nervous system. Enhancing… 
2013
2013
RGC-5 cells.
Our laboratory previously reported the generation of a retinal ganglion cell 5 (RGC-5) cell line with phenotypic expression of… 
2013
2013
Sigma-1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of mechanical allodynia in mice and neuropathic rats
2005
2005
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
ERG2, emopamil binding protein (EBP), and sigma-1 receptor (sigma(1)) are enzymes of sterol metabolism and an enzyme-related… 
Highly Cited
2004
Highly Cited
2004
Sigma1 receptor upregulation after chronic methamphetamine self-administration in rats: a study with yoked controls
RationaleSigma1 receptors (Sig-1R) are implicated in behavioral sensitization, conditioned place preference, and cellular… 
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