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sigma-1 receptor

Known as: receptor 1, sigma, sigma-1 receptors 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Receptors, sigma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Docking, Interaction Fingerprint, and Three-Dimensional Quantitative Structure–Activity Relationship (3D-QSAR) of Sigma1 Receptor Ligands, Analogs of the Neuroprotective Agent RC-33
The human Sigma1 receptor (S1R), which has been identified as a target with an important role in neuropsychological disorders… 
Review
2017
Review
2017
APEX2- tagging of Sigma 1-receptor indicates subcellular protein topology with cytosolic N-terminus and ER luminal C-terminus
Deciphering the role of any protein in a cell requires knowledge of the structure, subcellular localization, and the topological… 
2017
2017
APEX2-enhanced electron microscopy distinguishes sigma-1 receptor localization in the nucleoplasmic reticulum
The sigma-1 receptor (Sig1R) is an endoplasmic reticulum chaperonin that is attracting tremendous interest as a potential anti… 
2016
2016
Myristic acid hitchhiking on sigma-1 receptor to fend off neurodegeneration
Neurodegenerative diseases are linked to tauopathy as a result of cyclin dependent kinase 5 (cdk5) binding to its p25 activator… 
2014
2014
Overexpression of Sig1R is closely associated with tumor progression and poor outcome in patients with hilar cholangiocarcinoma
Nonopioid Sigma1 receptor (Sig1R), which regulates various metabolism functions, has been implicated in cancers; yet, its role in… 
2013
2013
Brain Sigma-1 Receptor Stimulation Improves Mental Disorder and Cardiac Function in Mice With Myocardial Infarction
Abstract: Mental disorder after myocardial infarction (MI) is reported by many epidemiological studies and is associated with a… 
2013
2013
Sigma-1 receptor concentration in plasma of patients with late-life depression: a preliminary study
Background Recently, the sigma-1 receptor has been shown to play a significant role in the neural transmission of mood by… 
Review
2012
Review
2012
[Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist].
Selective serotonin reuptake inhibitors (SSRIs) are known to reduce post-myocardial infarction (MI)-induced morbidity and… 
2005
2005
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.
ERG2, emopamil binding protein (EBP), and sigma-1 receptor (sigma(1)) are enzymes of sterol metabolism and an enzyme-related… 
Highly Cited
2004
Highly Cited
2004
Sigma1 receptor upregulation after chronic methamphetamine self-administration in rats: a study with yoked controls
RationaleSigma1 receptors (Sig-1R) are implicated in behavioral sensitization, conditioned place preference, and cellular… 
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