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sevirumab

Known as: SDZ-MSL-109, protovir, SDZ MSL 109 
 
National Institutes of Health

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Monoclonal Antibodies

Papers overview

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2014
2014
Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109.
Cytomegalovirus (CMV) is a widespread opportunistic pathogen that causes birth defects when transmitted transplacentally and… Expand
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2014
2014
In vitro affinity maturation of a natural human antibody overcomes a barrier to in vivo affinity maturation.
Antibodies isolated from human donors are increasingly being developed for anti-infective therapeutics. These antibodies undergo… Expand
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2013
2013
Extended SIW for <formula formulatype="inline"> <tex Notation="TeX">${\rm TE}_{m0}$</tex></formula> and <formula formulatype="inline"> <tex Notation="TeX">${\rm TE}_{0n}$</tex></formula> Modes and…
A substrate integrated guide which allows the propagation of both TEm0 and TE0n modes is presented, the Extended Substrate… Expand
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2012
2012
System verification of MSL Skycrane using an integrated ADAMS simulation
Mars Science Laboratory (MSL) will use the Skycrane architecture to execute final descent and landing maneuvers. The Skycrane… Expand
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2011
2011
Human cytomegalovirus escapes a naturally occurring neutralizing antibody by incorporating it into assembling virions.
Human cytomegalovirus (CMV) is a common but difficult to treat infection of immunocompromised patients. MSL-109 is a human… Expand
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2009
2009
Marginal Space Learning for Efficient Detection of 2D/3D Anatomical Structures in Medical Images
Recently, marginal space learning (MSL) was proposed as a generic approach for automatic detection of 3D anatomical structures in… Expand
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2002
2002
HIV and cytomegalovirus viral load and clinical outcomes in AIDS and cytomegalovirus retinitis patients: Monoclonal Antibody Cytomegalovirus Retinitis Trial.
OBJECTIVE To determine the association of cytomegalovirus (CMV) viremia with mortality and CMV retinitis progression in newly… Expand
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2001
2001
Randomized, placebo-controlled, double-blind study of a cytomegalovirus-specific monoclonal antibody (MSL-109) for prevention of cytomegalovirus infection after allogeneic hematopoietic stem cell…
MSL-109 is a monoclonal antibody specific to the cytomegalovirus (CMV) glycoprotein H with high neutralizing capacity. In a… Expand
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Review
2000
Review
2000
Therapeutic developments in cytomegalovirus retinitis.
The incidence of cytomegalovirus (CMV) retinitis in AIDS has declined significantly due to the use of highly active… Expand
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1997
1997
MSL-109 adjuvant therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: the Monoclonal Antibody Cytomegalovirus Retinitis Trial. The Studies of Ocular…
  • Archives of ophthalmology
  • 1997
OBJECTIVE To evaluate the efficacy and safety of an intravenous human monoclonal antibody to cytomegalovirus (CMV), MSL-109, as… Expand
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