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senicapoc

Known as: bis(4-fluorophenyl)phenylacetamide 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AcetamidesTrityl Compounds

Narrower (1)

ICA 17043

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
KCa3.1 Transgene Induction in Murine Intestinal Epithelium Causes Duodenal Chyme Accumulation and Impairs Duodenal Contractility
The epithelial intermediate-conductance calcium/calmodulin-regulated KCa3.1 channel is considered to be a regulator of intestine… 
2019
2019
S88 A human model of lung fibrosis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis
Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive and invariably lethal interstitial lung disease. Animal models… 
2017
2017
Senicapoc: Repurposing a Drug to Target Microglia KCa3.1 in Stroke
Stroke is the leading cause of serious long-term disability and the fifth leading cause of death in the United States. Treatment… 
2017
2017
Use of senicapoc for treatment of neuropathic pain
2016
2016
LATE-BREAKING ABSTRACT: KCa3.1 ion channel-blockade reduces pulmonary fibrotic responses via the inhibition of fibroblast proliferation
Drug development for idiopathic pulmonary fibrosis (IPF) has been limited due to poor translational efficacy of mouse-based in… 
2015
2015
The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity
ABSTRACT Senicapoc, a Gardos channel inhibitor, prevented erythrocyte dehydration in clinical trials of patients with sickle cell… 
2015
2015
Blockade of KCa 3 . 1 Attenuates Left Ventricular Remodeling after Experimental Myocardial Infarction
Background/Aims: After myocardial infarction (MI), cardiac fibrosis greatly contributes to left ventricular remodeling and heart… 
Review
2012
Review
2012
Drugs for preventing red blood cell dehydration in people with sickle cell disease.
BACKGROUND Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and… 
2008
2008
EFFICACY AND SAFETY OF THE GARDOS CHANNEL BLOCKER, SENICAPOC (ICA- 17043), IN PATIENTS WITH SICKLE CELL ANEMIA Running Title: Phase II senicapoc study in sickle cell anemia
(1174 articles) Red Cells • (3722 articles) Clinical Trials and Observations • Articles on similar topics can be found in the… 
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