selexipag

Known as: 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2018
051020102018

Papers overview

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2016
2016
AIM The aim of the present study was to explore the effect of hepatic or renal dysfunction on the pharmacokinetics (PK… (More)
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2016
2016
PURPOSE Selexipag is a new orally available nonprostanoid prostacyclin receptor agonist for the treatment of pulmonary arterial… (More)
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2016
2016
The aim of this single-center, open-label study was to assess the absolute bioavailability of an oral (tablet) versus intravenous… (More)
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2015
2015
PURPOSE Targeting the prostacyclin pathway is an effective treatment option for pulmonary arterial hypertension (PAH). Patients… (More)
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2015
2015
OBJECTIVE Selexipag is a novel, oral, selective prostacyclin (PGI2) receptor agonist in clinical development for the treatment of… (More)
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2015
2015
AIMS This study investigated the effect of a fixed dose combination of lopinavir/ritonavir on the pharmacokinetics (PK) of… (More)
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2015
2015
The effects of selexipag and its active metabolite ACT-333679 on cardiac repolarization were assessed in a thorough QT study as… (More)
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2014
2014
OBJECTIVE The objective of this study was to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of selexipag… (More)
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Highly Cited
2012
Highly Cited
2012
In this phase 2 proof-of-concept study we examined the safety and efficacy of selexipag, an orally available, selective… (More)
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2010
2010
Selexipag [2-{4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide] is an orally available… (More)
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