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NS-304

National Institutes of Health

Papers overview

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2019
2019
Abstract 1. The metabolism of the prostacyclin receptor agonist selexipag (NS-304; ACT-293987) and its active metabolite MRE-269… 
2018
2018
Patients with congenital diaphragmatic hernia (CDH) often suffer from severe pulmonary hypertension, and the choice of current… 
2018
2018
Abstract 1. This study examined the pharmacokinetics, distribution, metabolism and excretion of the selective prostacyclin… 
Highly Cited
2015
Highly Cited
2015
Prostacyclin controls cardiovascular function via activation of the prostacyclin receptor. Decreased prostacyclin production… 
Highly Cited
2008
Highly Cited
2008
2-{4-[(5,6-Diphenylpyrazin-2-yl)(isopropyl)amino]butoxy}-N-(methylsulfonyl)acetamide (NS-304) is an orally available, long-acting… 
Highly Cited
2007
Highly Cited
2007
Prostacyclin (PGI2) and its analogs are useful for the treatment of various vascular disorders, but their half-lives are too… 
2007
2007
Prostacyclin (PGI2) and its analogs are useful for the treatment of various vascular disorders, but their half-lives are too…