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selenodiglutathione

 
National Institutes of Health

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3 relations

Broader (2)

GlutathioneOrganoselenium Compounds
analogs & derivatives

Papers overview

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2011
2011
Selenodiglutathione uptake by the Saccharomyces cerevisiae vacuolar ATP-binding cassette transporter Ycf1p.
The Saccharomyces cerevisiae vacuolar ATP-binding cassette transporter Ycf1p is involved in heavy metal detoxification by… Expand
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Highly Cited
2010
Highly Cited
2010
Tellurium: an element with great biological potency and potential.
Tellurium has long appeared as a nearly 'forgotten' element in Biology, with most studies focusing on tellurite, tellurate and a… Expand
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Highly Cited
2004
Highly Cited
2004
Similarities between the abiotic reduction of selenite with glutathione and the dissimilatory reaction mediated by Rhodospirillum rubrum and Escherichia coli.
Various mechanisms have been proposed to explain the biological dissimilatory reduction of selenite (SeO3(2-)) to elemental… Expand
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Review
2001
Review
2001
Molecular mechanisms of cancer prevention by selenium compounds.
Selenium compounds that are chemopreventive in animal models inhibit cell growth and induce apoptosis in vitro, and this could… Expand
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1995
1995
AP-1 DNA-binding activity is inhibited by selenite and selenodiglutathione.
The binding of the transcription factor AP-1 to DNA has been shown to be modulated by redox control mechanisms. Selenite and… Expand
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Highly Cited
1995
Highly Cited
1995
Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols(*)
Human placenta thioredoxin reductase (HP-TR) in the presence of NADPH-catalyzed reduction of (15S)-hydroperoxy-(5Z),(8Z),11(Z),13… Expand
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1995
1995
The selenium metabolite selenodiglutathione induces cell death by a mechanism distinct from H2O2 toxicity.
Our previous studies have implicated the selenium metabolite selenodiglutathione (SDG) in the growth inhibitory effects of… Expand
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1994
1994
The selenium metabolite selenodiglutathione induces p53 and apoptosis: relevance to the chemopreventive effects of selenium?
Selenodiglutathione (SDG), the initial metabolite of selenite, is shown to be a more powerful inhibitor of cell growth in vitro… Expand
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1993
1993
Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione.
A human thioredoxin cDNA was modified to optimize Escherichia coli expression and subcloned into the plasmid pACA, a vector for… Expand
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1992
1992
Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase.
Selenium compounds like selenite (SeO3(2-) may form a covalent adduct with glutathione (GSH) in the form of selenodiglutathione… Expand
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