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sedoxantrone trihydrochloride

Known as: 2H-(1)Benzothiopyrano(4,3,2-cd)indazol-8-ol, 5-((2-aminoethyl)amino)-2-(2-(diethylamino)ethyl)-, Trihydrochloride, LEDOXANTRONE TRIHYDROCHLORIDE 
The trihydrochloride salt of the anthrapyrazole antineoplastic antibiotic sedoxantrone with potential antineoplastic activity. Sedoxantrone… 
National Institutes of Health

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CI 958

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2010
2010
Synthesis of water-soluble polyamine derivatives effective as N-methyl-D-aspartate receptor antagonists.
The novel water-soluble N-methyl-D-aspartate (NMDA) receptor antagonists, N-{4-[4-(4-Guanidinobutylamino)butylamino]butyl}-p… 
2007
2007
Modulation of P-glycoprotein by zosuquidar trihydrochloride.
P-glycoprotein (P-gp), a major contributor in multidrug resistance (MDR), is a cell surface drug efflux pump restricting the… 
2003
2003
Evaluation of copper chelation agents as anti-angiogenic therapy.
2000
2000
Circadian variation in the activity of the 5‐HT1B autoreceptor in the region of the suprachiasmatic nucleus, measured by microdialysis in the conscious freely‐moving rat
Intracerebral microdialysis was used to examine the function of the terminal 5‐hydroxytryptamine1B (5‐HT1B) autoreceptor in the… 
1999
1999
A phase II trial of CI-958 in patients with hormone-refractory prostate cancer
Purpose: To assess the antitumor activity of the benzothiopyranoindazole CI-958 {5-[(2-aminomethyl)amino]-2-[2-(diethylamino… 
1998
1998
DNA-drug interaction measurements using surface plasmon resonance.
The interactions of the drugs 2,7-bis[(diethylamino)-ethoxy]-fluoren-9-one dihydrochloride (Tilorone), 2,7-bis[(dipropylamino… 
1989
1989
Tolerance and pharmacokinetics of a new antiulcer compound in man after single oral doses.
5-[(2-Diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4- b]pyridine trihydrochloride (KW-5805) is a new antiulcer compound… 
1986
1986
Studies on antiviral agents. IV. Synthesis and in vitro antiviral activity of new N-palmitoylkanamycin A derivatives.
During the initial stages of this program1-3), we discovered that 1-N-(higher-acyl)-3"-N-substituted kanamycin A derivatives… 
1975
1975
Spasmolytic effect of 4-valeryl 4-(3-chlorophenyl) 1-[3-(4-methylpiperazine)-propyl)-piperidine trihydrochloride.
The purpose of this work was to check the effect of 4-valeryl 4-(3--chlorophenyl) 1-[3-(4-methylpiperazine)-propyl]-piperidine, a… 
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