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scytolone

Known as: 3,4-dihydro-3,6,8-trihydroxy-1-(2H)-naphthalenone, scytalone, 3,4-dihydro-3,6,8-trihydroxy-1(2H)naphthalenone 
National Institutes of Health

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Broader (1)

Naphthols

Papers overview

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2008
2008
First application of PCR-Luminex system for molecular diagnosis of fungicide resistance and species identification of fungal pathogens
Fungicide resistance in plant pathogens is often caused by a single point mutation in a gene encoding fungicide target proteins… 
Highly Cited
2004
Highly Cited
2004
Proteome analysis of rice blast fungus (Magnaporthe grisea) proteome during appressorium formation
We used two‐dimensional gel electrophoresis (2‐DE) to identify the proteins that are induced in the rice blast fungus Magnaporthe… 
2004
2004
Cloning, functional analysis and expression of a scytalone dehydratase gene (SCD1) involved in melanin biosynthesis of the phytopathogenic fungus Bipolaris oryzae
Abstract Scytalone dehydratase is involved in the production of fungal dihydroxynaphthalene melanin. We isolated and… 
2003
2003
Diagnosis of dehydratase inhibitors in melanin biosynthesis inhibitor (MBI-D) resistance by primer-introduced restriction enzyme analysis in scytalone dehydratase gene of Magnaporthe grisea.
We have established a simple diagnosis method for rice blast fungus resistant to MBI-D. This involves the preparation of PCR… 
Highly Cited
2000
Highly Cited
2000
Using an AraC-based three-hybrid system to detect biocatalysts in vivo
Recent methods to create large libraries of proteins have greatly advanced the discovery of proteins with novel functions… 
1999
1999
Catalytic mechanism of scytalone dehydratase: site-directed mutagenisis, kinetic isotope effects, and alternate substrates.
On the basis of the X-ray crystal structure of scytalone dehydratase complexed with an active center inhibitor [Lundqvist, T… 
1998
1998
2,3-Dihydro-2,5-dihydroxy-4H-benzopyran-4-one: a nonphysiological substrate for fungal melanin biosynthetic enzymes.
We have synthesized an alternate substrate for trihydroxynaphthalene reductase (3HNR) and scytalone dehydratase (SD), two enzymes… 
1997
1997
The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2).
Nuclear transport factor 2 (NTF2) facilitates protein transport into the nucleus and interacts with both the small Ras-like… 
1997
1997
Trihydroxynaphthalene reductase from Magnaporthe grisea: realization of an active center inhibitor and elucidation of the kinetic mechanism.
Active trihydroxynaphthalene reductase (3HNR) is essential for the biosynthesis of fungal melanin by Magnaporthe grisea and is a… 
1993
1993
Preliminary crystallographic studies on scytalone dehydratase from Magnaporthe grisea.
Magnaporthe grisea are pathogenic, directly penetrating fungi which cause rice blast disease. Isolated, non-pathogenic mutant… 
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