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satraplatin

Known as: (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum, bis-acetatoamminedichlorocyclohexylamine platinum(IV), platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43) 
An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Controlling anticancer drug activity and release on demand is very significant in cancer therapy. The photoactivated platinum(IV… Expand
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Highly Cited
2010
Highly Cited
2010
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… Expand
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Highly Cited
2010
Highly Cited
2010
Activating platinum with light: An inert platinum(IV) diazido complex trans, trans,trans-[Pt(N3)2(OH)2(py)2] becomes potently… Expand
Highly Cited
2009
Highly Cited
2009
PURPOSE This multinational, double-blind, randomized, placebo-controlled, phase III trial assessed the efficacy and tolerability… Expand
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Review
2008
Review
2008
Platinum drugs are major chemotherapeutic agents that are used alone or in combination with other systemic agents and/or… Expand
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Highly Cited
2008
Highly Cited
2008
The integrins alpha vbeta3 and alpha vbeta5 and the membrane-spanning surface protein aminopeptidase N (APN) are highly expressed… Expand
Review
2007
Review
2007
  • L. Kelland
  • Nature Reviews Cancer
  • 2007
  • Corpus ID: 205468214
The accidental discovery of the anticancer properties of cisplatin and its clinical introduction in the 1970s represent a major… Expand
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Highly Cited
2005
Highly Cited
2005
DNA damage often activates the p53–p21 pathway and causes G1-phase arrest in mammalian cells. Although there is ample evidence… Expand
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Highly Cited
1997
Highly Cited
1997
ion. The oxidative addition mechanism was originally proposed22i because of the lack of a strong rate dependence on polar factors… Expand
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Highly Cited
1995
Highly Cited
1995
Carboxylation of hydroxide coordinated to Pt(1V) by anhydrides, pyrocarbonates, and isocyanates to form the corresponding Pt(1V… Expand