Skip to search formSkip to main contentSkip to account menu

satraplatin

Known as: (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum, bis-acetatoamminedichlorocyclohexylamine platinum(IV), platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43) 
An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Antineoplastic AgentsOrganoplatinum Compounds

Narrower (2)

BMS-182751JM 216
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The use of polymeric platinum(IV) prodrugs to deliver multinuclear platinum(II) drugs with reduced systemic toxicity and enhanced antitumor efficacy.
Highly Cited
2007
Highly Cited
2007
Preclinical antitumor activity of the oral platinum analog satraplatin
PurposeSatraplatin is an orally available platinum analog. The purpose of this study was to better characterize satraplatin’s… 
Review
2007
Review
2007
Taxane refractory prostate cancer.
Review
2007
Review
2007
Chemotherapy for the treatment of hormone‐refractory prostate cancer
Aims:  This review aims at analysing the published literature on chemotherapy for hormone‐refractory prostate cancer (HRPC) to… 
Review
2005
Review
2005
Future directions in the treatment of androgen-independent prostate cancer.
2002
2002
Direct addition of alcohols to organonitriles activated by ligation to a platinum(IV) center.
Treatment of trans-[PtCl(4)(RCN)(2)] (R = Me, Et) with R'OH (R' = Me, Et, n-Pr, i-Pr, n-Bu) at 45 degrees C in all cases allowed… 
2001
2001
Five-coordinate trispyrazolylborate dihydridosilyl platinum(IV) complexes.
Highly Cited
2000
Highly Cited
2000
Iminoacylation. 3. Formation of platinum(IV)-based metallaligands due to facile one-end addition of vic-dioximes to coordinated organonitriles.
The reaction of vic-dioximes with the organonitrile platinum(IV) complexes trans-[PtCl4(RCN)2] (R = Me, CH2Ph, Ph, vic-dioxime… 
1991
1991
An unexpected biotransformation pathway for tetrachloro-(d,l-trans)-1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) in the L1210 cell line.
Tetrachloro(d,l-trans)-1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) has been considered a prodrug which would be converted… 
1988
1988
Comparative toxicity and renal distribution of the platinum analogs tetraplatin, CHIP, and cisplatin at equimolar doses in the Fischer 344 rat.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)