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satraplatin
Known as:
(OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum
, bis-acetatoamminedichlorocyclohexylamine platinum(IV)
, platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43)
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An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged…
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National Institutes of Health
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Related topics
Related topics
5 relations
Broader (2)
Antineoplastic Agents
Organoplatinum Compounds
Narrower (2)
BMS-182751
JM 216
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
In vivo multimodality imaging and cancer therapy by near-infrared light-triggered trans-platinum pro-drug-conjugated upconverison nanoparticles.
Yunlu Dai
,
Haihua Xiao
,
+8 authors
Jun Lin
Journal of the American Chemical Society
2013
Corpus ID: 23249093
Controlling anticancer drug activity and release on demand is very significant in cancer therapy. The photoactivated platinum(IV…
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Highly Cited
2010
Highly Cited
2010
The status of platinum anticancer drugs in the clinic and in clinical trials.
N. Wheate
,
Shonagh Walker
,
Gemma E Craig
,
Rabbab Oun
Dalton transactions
2010
Corpus ID: 205766376
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian…
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Highly Cited
2010
Highly Cited
2010
A potent trans-diimine platinum anticancer complex photoactivated by visible light.
N. J. Farrer
,
J. Woods
,
+5 authors
P. Sadler
Angewandte Chemie
2010
Corpus ID: 1610334
Activating platinum with light: An inert platinum(IV) diazido complex trans, trans,trans-[Pt(N3)2(OH)2(py)2] becomes potently…
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Highly Cited
2009
Highly Cited
2009
Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: the SPARC trial…
C. Sternberg
,
D. Petrylak
,
+16 authors
M. Rozencweig
Journal of clinical oncology : official journal…
2009
Corpus ID: 16095303
PURPOSE This multinational, double-blind, randomized, placebo-controlled, phase III trial assessed the efficacy and tolerability…
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Review
2009
Review
2009
Unusual DNA binding modes for metal anticancer complexes.
Ana M. Pizarro
,
P. Sadler
Biochimie
2009
Corpus ID: 9205920
Review
2008
Review
2008
Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue
H. Choy
,
Clinton Park
,
M. Yao
Clinical Cancer Research
2008
Corpus ID: 1701593
Platinum drugs are major chemotherapeutic agents that are used alone or in combination with other systemic agents and/or…
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Highly Cited
2008
Highly Cited
2008
Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature.
S. Mukhopadhyay
,
C. Barnés
,
A. Haskel
,
S. Short
,
Katie R Barnes
,
S. Lippard
Bioconjugate chemistry
2008
Corpus ID: 21313697
The integrins alpha vbeta3 and alpha vbeta5 and the membrane-spanning surface protein aminopeptidase N (APN) are highly expressed…
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Review
2007
Review
2007
The resurgence of platinum-based cancer chemotherapy
L. Kèlland
Nature Reviews Cancer
2007
Corpus ID: 205468214
The accidental discovery of the anticancer properties of cisplatin and its clinical introduction in the 1970s represent a major…
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Highly Cited
1997
Highly Cited
1997
ACTIVATION OF C-H BONDS BY METAL COMPLEXES
Alexander E. Shilov and
,
G. B. Shul’pin
1997
Corpus ID: 95480843
ion. The oxidative addition mechanism was originally proposed22i because of the lack of a strong rate dependence on polar factors…
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Highly Cited
1995
Highly Cited
1995
Carboxylation of Kinetically Inert Platinum(IV) Hydroxy Complexes. An Entr.acte.ee into Orally Active Platinum(IV) Antitumor Agents.
C. Giandomenico
,
M. Abrams
,
+5 authors
J. D. Higgins
Inorganic chemistry
1995
Corpus ID: 437501
Carboxylation of hydroxide coordinated to Pt(1V) by anhydrides, pyrocarbonates, and isocyanates to form the corresponding Pt(1V…
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