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sabcomeline

Known as: alpha-(methylimino)-1-azabicyclo(2.2.2)octane-3-acetonitrile 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
In functional assay assessments using the five muscarinic receptor subtypes, a second generation of muscarinic M(1)-preferring… Expand
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2008
2008
We have demonstrated that the main metabolite of clozapine, N-desmethylclozapine, has a significant role in the ability of… Expand
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Highly Cited
2005
Highly Cited
2005
Prepulse inhibition (PPI) of the acoustic startle reflex is a sensorimotor gating process known to be deficient in a number of… Expand
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2001
2001
  • P. Stengel, M. Cohen
  • The Journal of pharmacology and experimental…
  • 2001
  • Corpus ID: 31263878
Carbamylcholine, a nonselective muscarinic receptor agonist, and sabcomeline and xanomeline, functional M(1) receptor-selective… Expand
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2001
2001
In functional pharmacological assays, talsaclidine has been described as a functionally preferential M1 agonist with full… Expand
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Highly Cited
1999
Highly Cited
1999
This study describes the pharmacological comparison of the muscarinic partial agonists sabcomeline, xanomeline and milameline at… Expand
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1999
1999
We have investigated the pharmacology of the functionally selective muscarinic M1 receptor partial agonist, sabcomeline [SB… Expand
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1999
1999
Research into and development of selective muscarinic receptor agonists for the treatment of Alzheimer’s disease is based on the… Expand
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1998
1998
Sabcomeline (SB‐202026, 0.03 mg kg−1, p.o.), a potent and functionally selective M1 receptor partial agonist, caused a… Expand
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1998
1998
Abstract Sabcomeline, (SB-202026 [R-(Z)-α-(methoxyimino)-1-azabicyclo [2.2.2] octane-3-acetonitrile]), a functionally selective… Expand
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