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ruffle

Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. [ISBN:0124325653]
National Institutes of Health

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2011
2011
Reversible interactions between cytosolic proteins and membrane lipids such as phosphoinositides play important roles in membrane… Expand
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Highly Cited
2007
Highly Cited
2007
Cell motility proceeds by cycles of edge protrusion, adhesion, and retraction. Whether these functions are coordinated by… Expand
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2006
2006
The Wiskott-Aldrich syndrome protein (WASP) family activates the Arp2/3 complex leading to the formation of new actin filaments… Expand
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Highly Cited
2006
Highly Cited
2006
Palladin is a widely expressed phosphoprotein that plays an important role in organizing the actin cytoskeleton. Palladin is… Expand
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Highly Cited
2003
Highly Cited
2003
Cell migration is driven by actin polymerization at the leading edge of lamellipodia, where WASP family verprolin-homologous… Expand
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2003
2003
SKIP (skeletal muscle and kidney enriched inositol phosphatase) is a recently identified phosphatidylinositol 3,4,5-trisphosphate… Expand
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2003
2003
Growth factors initiate cytoskeletal rearrangements tightly coordinated with nuclear signaling events. We hypothesized that the… Expand
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Highly Cited
1998
Highly Cited
1998
The actin cytoskeleton maintains the cellular architecture and mediates cell movements. To explore actin cytoskeletal dynamics… Expand
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Highly Cited
1993
Highly Cited
1993
Treatment with hepatocyte growth factor/scatter factor (HGF/SF) rapidly induced the formation of conspicuous circular ruffles on… Expand
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Highly Cited
1970
Highly Cited
1970
Abstract Various aspects of the behaviour of the lamellar projections termed “ruffles” that appear at the leading end of… Expand
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