FAQ

ruffle membrane

Known as: membrane ruffle 
The portion of the plasma membrane surrounding a ruffle. [GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2018
02419882018

Related topics

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2 relations

Broader (1)

ruffle
ruffle assembly

Related mentions per year

Related mentions per year

1970-2018
197019801990200020102020
ruffle membrane
ruffle assembly
ruffle

Papers overview

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2011
2011
The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association.
Membrane ruffling is the formation of actin rich membrane protrusions, essential for cell motility. The exact mechanism of… (More)
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2010
2010
Lamellipodium extension and membrane ruffling require different SNARE-mediated trafficking pathways
Intracellular membrane traffic is an essential component of the membrane remodeling that supports lamellipodium extension during… (More)
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Highly Cited
2007
Highly Cited
2007
Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis.
Histone deacetylase 6 (HDAC6) is a cytoplasmic deacetylase that uniquely catalyzes alpha-tubulin deacetylation and promotes cell… (More)
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2003
2003
SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation.
Skeletal muscle and kidney enriched inositol phosphatase (SKIP) is an inositol polyphosphate 5-phosphatase that hydrolyzes… (More)
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2003
2003
Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic…
SKIP (skeletal muscle and kidney enriched inositol phosphatase) is a recently identified phosphatidylinositol 3,4,5-trisphosphate… (More)
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2003
2003
Requirement of autophosphorylated tyrosine 992 of EGF receptor and its docking protein phospholipase C gamma 1 for membrane ruffle formation.
Stimulation of the epidermal growth factor receptor (EGFR) produces membrane ruffles through the small G protein Rac1; however… (More)
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Highly Cited
2002
Highly Cited
2002
ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts
The small GTPase Rho acts on two effectors, ROCK and mDia1, and induces stress fibers and focal adhesions. However, how ROCK and… (More)
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2000
2000
Vasodilator-stimulated phosphoprotein is involved in stress-fiber and membrane ruffle formation in endothelial cells.
Vasodilator-stimulated phosphoprotein (VASP) is highly expressed in vascular endothelial cells, where it has been implicated in… (More)
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Highly Cited
1994
Highly Cited
1994
Preferential interaction of Salmonella typhimurium with mouse Peyer's patch M cells.
We have used a mouse Peyer's patch gut loop model to investigate the role of the intestinal membranous epithelial (M) cells in… (More)
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1993
1993
Production of a unique antibody specific for membrane ruffles and its use to characterize the behavior of two distinct types of ruffles
I have produced a new monoclonal antibody, YF-169, against membrane ruffle specific 55-kD protein. YF-169 stained membrane… (More)
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