ruffle assembly

Known as: membrane ruffle formation, membrane ruffling 
The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the… (More)
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
We examined the spatio-temporal activity of RhoA in migrating cells and growth factor-stimulated cells by using probes based on… (More)
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Highly Cited
2000
Highly Cited
2000
Neural Wiskott-Aldrich syndrome protein (N-WASP) functions in several intracellular events including filopodium formation… (More)
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Highly Cited
2000
Highly Cited
2000
Sphingosine-1-phosphate (S1P) is a bioactive lysophospholipid that induces a variety of biological responses in diverse cell… (More)
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Highly Cited
1999
Highly Cited
1999
Cell migration and wound contraction requires assembly of actin into a functional myosin motor unit capable of generating force… (More)
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Highly Cited
1998
Highly Cited
1998
S. typhimurium stimulates signaling pathways leading to membrane ruffling, actin cytoskeleton rearrangements, and nuclear… (More)
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Highly Cited
1997
Highly Cited
1997
Specific pathways linking heterotrimeric G proteins and Fcgamma receptors to the actin-based cytoskeleton are poorly understood… (More)
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Highly Cited
1996
Highly Cited
1996
The RAS guanine nucleotide binding proteins activate multiple signaling events that regulate cell growth and differentiation. In… (More)
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Highly Cited
1995
Highly Cited
1995
RHO-LIKE GTPases have been implicated in the regulation of the actin cytoskeleton which controls the morphology, adhesion and… (More)
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Review
1994
Review
1994
One of the earliest structural changes observed in cells in response to many extracellular factors is membrane ruffling: the… (More)
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Highly Cited
1992
Highly Cited
1992
The function of rac, a ras-related GTP-binding protein, was investigated in fibroblasts by microinjection. In confluent serum… (More)
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