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ruffle assembly

Known as: membrane ruffle formation, membrane ruffling 
The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the… Expand
National Institutes of Health

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Highly Cited
2000
Highly Cited
2000
Neural Wiskott-Aldrich syndrome protein (N-WASP) functions in several intracellular events including filopodium formation… Expand
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Highly Cited
1998
Highly Cited
1998
S. typhimurium stimulates signaling pathways leading to membrane ruffling, actin cytoskeleton rearrangements, and nuclear… Expand
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Highly Cited
1997
Highly Cited
1997
The pathways by which mammalian Ras proteins induce cortical actin rearrangement and cause cellular transformation are… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The Rho family GTPases Cdc42, Rac1 and RhoA regulate the reorganization of the actin cytoskeleton induced by… Expand
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Highly Cited
1997
Highly Cited
1997
Specific pathways linking heterotrimeric G proteins and Fcγ receptors to the actin-based cytoskeleton are poorly understood. To… Expand
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Highly Cited
1996
Highly Cited
1996
The RAS guanine nucleotide binding proteins activate multiple signaling events that regulate cell growth and differentiation. In… Expand
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Highly Cited
1995
Highly Cited
1995
RHO-LIKE GTPases have been implicated in the regulation of the actin cytoskeleton which controls the morphology, adhesion and… Expand
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Highly Cited
1995
Highly Cited
1995
The small GTP-binding proteins, rho and rac, control signal transduction pathways that link growth factor receptors to the… Expand
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Highly Cited
1994
Highly Cited
1994
BACKGROUND There is substantial evidence that phosphoinositide 3-kinase (PI 3-kinase) is a critical component of signalling… Expand
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Highly Cited
1992
Highly Cited
1992
The function of rac, a ras-related GTP-binding protein, was investigated in fibroblasts by microinjection. In confluent serum… Expand
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