Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

roquinimex

Known as: 1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide, 3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-, N-Phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide 
A quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits endothelial cell proliferation, migration, and basement… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
5-Chloro-N-ethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-3-quinolinecarboxamide (laquinimod, 2) is an oral drug in clinical… Expand
Highly Cited
2004
Highly Cited
2004
The new orally active drug laquinimod (ABR-215062) was evaluated in experimental autoimmune encephalomyelitis (EAE) in the Lewis… Expand
Highly Cited
2004
Highly Cited
2004
Roquinimex-related 3-quinolinecarboxamide derivatives were prepared and evaluated for treatment of autoimmune disorders. The… Expand
  • figure 1
  • figure 2
  • table 2
  • table 3
Highly Cited
2002
Highly Cited
2002
A new orally active drug, laquinimod (ABR-215062), was shown to completely inhibit the development of murine acute experimental… Expand
Review
2002
Review
2002
The therapy for multiple sclerosis (MS) has changed dramatically over the past decade. Recent immunobiological findings and… Expand
Highly Cited
2000
Highly Cited
2000
Objective: To determine whether linomide (roquinimex) is better than placebo in slowing the time to confirmed clinical worsening… Expand
  • table 1
  • table 2
  • table 3
Highly Cited
2000
Highly Cited
2000
Objective: To determine the safety and efficacy of roquinimex (linomide) in the management of relapsing-remitting and secondary… Expand
  • figure 1
  • figure 2
2000
2000
The absorption and disposition of roquinimex (Linomide®) were studied in four male and two female healthy volunteers. The… Expand
1999
1999
Unmanipulated autologous bone marrow transplant (ABMT) offers patients with chronic myelogenous leukemia (CML) a long-term… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Highly Cited
1998
Highly Cited
1998
BACKGROUND Tumor-associated macrophages (TAMs) can either promote angiogenesis (i.e., the formation of new blood vessels) in… Expand
  • table 1
  • table 3
  • figure 1