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rolofylline
Known as:
1,3-dipropyl-8-(3-noradamantyl)xanthine
, 1,3-dipropyl-8-(tricyclo(3.3.1.0(sup 3,7))non-3-yl)-3,7-dihydro-1h-purine-2,6-dione
, 1,3-DNAX
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Diuretics
Xanthines
Narrower (2)
KW-3902
MK 7418
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
The disconnect between phase II and phase III trials of drugs for heart failure
M. Vaduganathan
,
S. Greene
,
A. Ambrosy
,
M. Gheorghiade
,
J. Butler
Nature Reviews Cardiology
2013
Corpus ID: 21135760
Hospitalization for heart failure (HF) is a clinical entity associated with high postdischarge morbidity and mortality, yet few…
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2013
2013
Computational Profiling of Bioactive Compounds Using a Target-Dependent Composite Workflow
Jamel Meslamani
,
R. Bhajun
,
F. Martz
,
D. Rognan
Journal of Chemical Information and Modeling
2013
Corpus ID: 31031906
Computational target fishing is a chemoinformatic method aimed at determining main and secondary targets of bioactive compounds…
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2010
2010
Haemodynamic effects of rolofylline in the treatment of patients with heart failure and impaired renal function
P. Ponikowski
,
V. Mitrović
,
+9 authors
M. Metra
European Journal of Heart Failure
2010
Corpus ID: 19203701
The direct effects of adenosine A1 receptor antagonists on haemodynamic parameters in patients with acute heart failure (HF…
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2002
2002
Role of Adenosine A1 Receptor in Angiotensin II- and Norepinephrine-Induced Renal Vasoconstriction
Y. Aki
,
A. Nishiyama
,
A. Miyatake
,
S. Kimura
,
M. Kohno
,
Y. Abe
Journal of Pharmacology and Experimental…
2002
Corpus ID: 14048403
We investigated the contributions of adenosine A1 receptors to angiotensin II- and norepinephrine-induced renal vasoconstriction…
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2000
2000
[Effect of KW-3902, a selective adenosine A1-receptor antagonist, on accumulation of gentamicin in the proximal renal tubules in rats].
K. Yao
Yakugaku zasshi : Journal of the Pharmaceutical…
2000
Corpus ID: 36010836
Adenosine A1-receptor antagonists have been previously shown to possess protective effects in several nephrotoxic models of acute…
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2000
2000
Effect of the selective adenosine A1-receptor antagonist KW-3902 on tubuloglomerular feedback in radiocontrast-media-induced nephropathy in rats with chronic nitric oxide deficiency.
K. Yao
,
N. Heyne
,
H. Osswald
Japanese Journal of Pharmacology
2000
Corpus ID: 1266483
To study the possible mechanism of renoprotective effects of adenosine A1-receptor antagonist against radiocontrast media (RCM…
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1996
1996
Effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), an adenosine A1-receptor antagonist, on urinary excretions of various electrolytes in rats.
K. Nagashima
,
A. Karasawa
Biological and Pharmaceutical Bulletin
1996
Corpus ID: 22414819
We examined the effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), an adenosine A1-receptor antagonist, on urine…
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1994
1994
Effects of KW-3902, a novel adenosine A1-receptor antagonist, on cephaloridine-induced acute renal failure in rats.
K. Nagashima
,
H. Kusaka
,
Kiyoshi Sato
,
Akira Karasawa
Japanese Journal of Pharmacology
1994
Corpus ID: 8406728
We investigated the possible renal protective effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), a selective and…
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1993
1993
Diuretic effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), a novel adenosine A1 receptor antagonist, in conscious dogs.
T. Kobayashi
,
H. Mizumoto
,
A. Karasawa
Biological and Pharmaceutical Bulletin
1993
Corpus ID: 23017331
The diuretic effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine), a novel adenosine A1 receptor antagonist, were…
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1993
1993
Effects of adenosine A1-agonist and -antagonist on urinary volume and Na excretion in IAP-treated and non-treated rats.
H. Mizumoto
,
A. Karasawa
Japanese Journal of Pharmacology
1993
Corpus ID: 10749549
Effects of an adenosine A1-receptor agonist and antagonist were determined in pertussis toxin (IAP)-treated and non-treated rats…
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