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robalzotan
Known as:
3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen tartrate monohydrate
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Benzopyrans
Narrower (1)
NAD 299
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Synthesis of robalzotan, ebalzotan, and rotigotine precursors via the stereoselective multienzymatic cascade reduction of α,β-unsaturated aldehydes.
E. Brenna
,
F. Gatti
,
L. Malpezzi
,
D. Monti
,
F. Parmeggiani
,
A. Sacchetti
The Journal of organic chemistry
2013
Corpus ID: 9652410
A stereoselective synthesis of bicyclic primary or secondary amines, based on tetralin or chroman structural moieties, is…
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2006
2006
Robalzotan (NAD‐299), a Novel Selective 5‐HT 1A Receptor Antagonist
S. Ross
,
S. Thorberg
,
+5 authors
G. Öjteg
2006
Corpus ID: 10098488
5-Hydroxytryptamine (5-HT, serotonin) is widely distributed in the serotonergic neurons in the CNS with the cell bodies in the…
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2005
2005
Central serotonergic control of cardiovascular reflexes.
D. O. Kellett
2005
Corpus ID: 76861510
Central serotonergic neurones control reflex parasympathetic outflow to the heart, airways and bladder in a number of species…
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Highly Cited
2003
Highly Cited
2003
Selective 5-HT1A Antagonists WAY 100635 and NAD-299 Attenuate the Impairment of Passive Avoidance Caused by Scopolamine in the Rat
I. Misane
,
S. Ögren
Neuropsychopharmacology
2003
Corpus ID: 21091244
Systemic administration of the muscarinic-receptor antagonists atropine and scopolamine produces cognitive deficits in humans…
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2003
2003
Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain
B. Andrée
,
A. Hedman
,
S. Thorberg
,
D. Nilsson
,
C. Halldin
,
L. Farde
Psychopharmacology
2003
Corpus ID: 21647381
RationaleThe serotonin 5-HT1A receptor has been ascribed a putative role in the pathophysiology and drug treatment of depression…
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Review
2000
Review
2000
Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development.
B. Andrée
,
C. Halldin
,
S. Thorberg
,
J. Sandell
,
L. Farde
Nuclear medicine and biology
2000
Corpus ID: 25591657
2000
2000
PET-Determination of Robalzotan (NAD-299) Induced 5-HT1A Receptor Occupancy in the Monkey Brain
L. Farde
,
B. Andrée
,
N. Ginovart
,
C. Halldin
,
S. Thorberg
Neuropsychopharmacology
2000
Corpus ID: 27299144
2000
2000
Robalzotan AstraZeneca.
H. A. Mucke
Current opinion in investigational drugs
2000
Corpus ID: 46577360
AstraZeneca (formerly Astra) is developing robalzotan, a 5-HT1A antagonist, for the potential treatment of depression and anxiety…
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1999
1999
The 5-HT(1A) receptor antagonist robalzotan completely reverses citalopram-induced inhibition of serotonergic cell firing.
L. Arborelius
,
C. Wallsten
,
S. Ahlénius
,
T. Svensson
European journal of pharmacology
1999
Corpus ID: 39752087
1998
1998
Receptor binding characteristics of [3H]NAD-299, a new selective 5-HT1A receptor antagonist.
E. Jerning
,
G. Svantesson
,
N. Mohell
European journal of pharmacology
1998
Corpus ID: 4613162
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