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robalzotan

Known as: 3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen tartrate monohydrate 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
A stereoselective synthesis of bicyclic primary or secondary amines, based on tetralin or chroman structural moieties, is… Expand
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2006
2006
5-Hydroxytryptamine (5-HT, serotonin) is widely distributed in the serotonergic neurons in the CNS with the cell bodies in the… Expand
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2005
2005
Central serotonergic neurones control reflex parasympathetic outflow to the heart, airways and bladder in a number of species… Expand
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Highly Cited
2003
Highly Cited
2003
Systemic administration of the muscarinic-receptor antagonists atropine and scopolamine produces cognitive deficits in humans… Expand
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2003
2003
RationaleThe serotonin 5-HT1A receptor has been ascribed a putative role in the pathophysiology and drug treatment of depression… Expand
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2000
2000
The serotonin 5-hydroxytryptamine-1A (5-HT1A) receptor subtype is of central interest in research, particularly in the area of… Expand
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2000
2000
  • H. A. Mucke
  • Current opinion in investigational drugs
  • 2000
  • Corpus ID: 46577360
AstraZeneca (formerly Astra) is developing robalzotan, a 5-HT1A antagonist, for the potential treatment of depression and anxiety… Expand
Review
2000
Review
2000
Positron-emission tomography (PET) provides potential in neuropsychiatric drug development by expanding knowledge of drug action… Expand
1999
1999
5-HT(1A) receptor antagonists have been suggested to increase the efficacy of selective serotonin (5-hydroxytryptamine; 5-HT… Expand
1998
1998
In vitro receptor binding properties of the novel tritiated 5-hydroxytryptamine1A (5-HT1A) receptor antagonist (R)-3-N,N… Expand