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rilotumumab

Known as: Anti-HGF Monoclonal Antibody AMG 102, Fully Human Anti-HGF Monoclonal Antibody AMG 102 
A fully human IgG2 monoclonal antibody directed against the human hepatocyte growth factor (HGF) with potential antineoplastic activity. Anti-HGF… Expand
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
BACKGROUND Rilotumumab is a fully human monoclonal antibody that selectively targets the ligand of the MET receptor, hepatocyte… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Dysregulation of the hepatocyte growth factor (HGF)/MET pathway promotes tumour growth and metastasis. Rilotumumab is… Expand
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Highly Cited
2014
Highly Cited
2014
PURPOSE Panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody (mAb), has demonstrated efficacy in… Expand
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2014
2014
METHODS Thirty patients with proven colorectal cancer prospectively underwent integrated 18F-FDG PET/DCE-CT to assess the… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND This study evaluated the tolerability and antitumor activity of AMG 386, a peptibody (a peptide Fc fusion) that… Expand
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Highly Cited
2011
Highly Cited
2011
This phase II study evaluated the efficacy and safety of AMG 102 (rilotumumab), a fully human monoclonal antibody against… Expand
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Highly Cited
2009
Highly Cited
2009
Accuracy and run-time play an important role in medical diagnostics and research as well as in the field of neuroscience. In… Expand
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Highly Cited
2008
Highly Cited
2008
The vanilloid receptor TRPV1 has been identified as a molecular target for the treatment of pain associated with inflammatory… Expand
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Highly Cited
2008
Highly Cited
2008
Co-crystals are relatively novel in the pharmaceutical field and are not reported extensively. AMG 517 is an insoluble small… Expand
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Highly Cited
2003
Highly Cited
2003
Current treatment of secondary hyperparathyroidism in chronic kidney failure with calcium and active vitamin D is potentially… Expand
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