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rilotumumab

Known as: Anti-HGF Monoclonal Antibody AMG 102, Fully Human Anti-HGF Monoclonal Antibody AMG 102 
A fully human IgG2 monoclonal antibody directed against the human hepatocyte growth factor (HGF) with potential antineoplastic activity. Anti-HGF… 
National Institutes of Health

Related topics

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Narrower (1)

AMG 102
HGF protein, humanNCIt Antineoplastic Agent Terminologyantigen binding

Broader (1)

Monoclonal Antibodies

Papers overview

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Highly Cited
2020
Highly Cited
2020
Controlling Enamel Remineralization by Amyloid‐Like Amelogenin Mimics
In situ regeneration of the enamel‐like structure of hydroxyapatite (HAp) crystals under oral conditions is significant for… 
Highly Cited
2015
Highly Cited
2015
Phase III, randomized, double-blind, multicenter, placebo (P)-controlled trial of rilotumumab (R) plus epirubicin, cisplatin and capecitabine (ECX) as first-line therapy in patients (pts) with…
4000 Background: R is a fully human monoclonal antibody to hepatocyte growth factor. A phase 2 study showed improved overall… 
Highly Cited
2014
Highly Cited
2014
Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b…
2014
2014
Correlation of Intra-Tumor 18F-FDG Uptake Heterogeneity Indices with Perfusion CT Derived Parameters in Colorectal Cancer
Application of textural features analysis to 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) images has been… 
Highly Cited
2012
Highly Cited
2012
AMG 386 in combination with sorafenib in patients with metastatic clear cell carcinoma of the kidney
This study evaluated the tolerability and antitumor activity of AMG 386, a peptibody (a peptide Fc fusion) that neutralizes the… 
Highly Cited
2012
Highly Cited
2012
Targeted MET Inhibition in Castration-Resistant Prostate Cancer: A Randomized Phase II Study and Biomarker Analysis with Rilotumumab plus Mitoxantrone and Prednisone
Purpose: To evaluate the efficacy, safety, biomarkers, and pharmacokinetics of rilotumumab, a fully human, monoclonal antibody… 
2012
2012
Characterization of microRNAs Expressed during Secondary Wall Biosynthesis in Acacia mangium
MicroRNAs (miRNAs) play critical regulatory roles by acting as sequence specific guide during secondary wall formation in woody… 
Highly Cited
2008
Highly Cited
2008
The co-crystal approach to improve the exposure of a water-insoluble compound: AMG 517 sorbic acid co-crystal characterization and pharmacokinetics.
Co-crystals are relatively novel in the pharmaceutical field and are not reported extensively. AMG 517 is an insoluble small… 
Highly Cited
2003
Highly Cited
2003
Estradiol in the male rat amygdala facilitates mounting but not ejaculation
Highly Cited
1989
Highly Cited
1989
1-O-hexadecyl-2-Q-methylglycerol, a novel inhibitor of protein kinase C, inhibits the respiratory burst in human neutrophils.
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