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ribonucleoside-diphosphate reductase activity

Known as: ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor, RNR, 2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity 
Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin… 
National Institutes of Health

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Related topics

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Ribonucleotide Reductase

Broader (1)

ribonucleotide reductase activity

Papers overview

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2014
2014
Re-evaluation of the inheritance for root-knot nematode resistance in the Upland cotton germplasm line M-120 RNR revealed two epistatic QTLs conferring resistance
We report a second major QTL for root-knot nematode resistance in the highly resistant Upland cotton line M-120RNR and show… 
2014
2014
Effects of terminal dimethylation and metal coordination of proline-2-formylpyridine thiosemicarbazone hybrids on lipophilicity, antiproliferative activity, and hR2 RNR inhibition.
The nickel(II), copper(II), and zinc(II) complexes of the proline-thiosemicarbazone hybrids 3-methyl-(S)-pyrrolidine-2… 
2012
2012
Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format
Ribonucleotide reductase (RNR) catalyzes reduction of the four different ribonucleotides to their corresponding… 
Highly Cited
2011
Highly Cited
2011
Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.
2008
2008
Clinical significance of redundant nerve roots of the cauda equina in lumbar spinal stenosis
Highly Cited
2007
Highly Cited
2007
NrdR Controls Differential Expression of the Escherichia coli Ribonucleotide Reductase Genes
ABSTRACT Escherichia coli possesses class Ia, class Ib, and class III ribonucleotide reductases (RNR). Under standard laboratory… 
2007
2007
The synergistic interaction of gemcitabine and cytosine arabinoside with the ribonucleotide reductase inhibitor triapine is schedule dependent.
Highly Cited
2006
Highly Cited
2006
QTL mapping for resistance to root-knot nematodes in the M-120 RNR Upland cotton line (Gossypium hirsutum L.) of the Auburn 623 RNR source
Root-knot nematodes Meloidogyne incognita (Kofoid and White) can cause severe yield loss in cotton (Gossypium hirsutum L.). The… 
2000
2000
Cysteines Involved in Radical Generation and Catalysis of Class III Anaerobic Ribonucleotide Reductase
Class III ribonucleotide reductase (RNR) is an anaerobic glycyl radical enzyme that catalyzes the reduction of ribonucleotides to… 
1998
1998
Molecular characterization of tobacco ribonucleotide reductase RNR1 and RNR2 cDNAs and cell cycle-regulated expression in synchronized plant cells
Eukaryotic ribonucleotide reductase (RNR), the enzyme involved in the synthesis of the deoxyribonucleotides, consists of two R1… 
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