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response to doxorubicin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2017
02419782017

Papers overview

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2017
2017
Investigation of Mitochondrial Metabolic Response to Doxorubicin in Prostate Cancer Cells: An NADH, FAD and Tryptophan FLIM Assay
Prostate cancer (PCa) is one of the leading cancers in men in the USA. Lack of experimental tools that predict therapy response… (More)
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2016
2016
Formation of mitochondrial-derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system.
KEY POINTS Mitochondrial-derived vesicle (MDV) formation occurs under baseline conditions and is rapidly upregulated in response… (More)
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2015
2015
MicroRNA Profile in Response to Doxorubicin Treatment in Breast Cancer.
UNLABELLED Chemotherapy treatment is the standard in triple negative breast cancers, a cancer subgroup which lacks a specific… (More)
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2014
2014
Maspin influences response to doxorubicin by changing the tumor microenvironment organization.
Altered degradation and deposition of extracellular matrix are hallmarks of tumor progression and response to therapy. From a… (More)
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2014
2014
ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment
We have recently reported that the homologous Rho kinases, ROCK1 and ROCK2, play different roles in regulating stress-induced… (More)
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2013
2013
Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways.
AIMS Doxorubicin causes damage to the heart, often leading to irreversible cardiomyopathy, which is fatal. Reactive oxygen… (More)
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2012
2012
Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.
To maintain genomic integrity DNA damage response (DDR), signaling pathways have evolved that restrict cellular replication and… (More)
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2011
2011
ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.
ERp29 is an endoplasmic reticulum (ER) luminal protein with a putative secretion factor/escort chaperone function. Accumulated… (More)
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2002
2002
Nuclear Factor- B Protects the Liver against Genotoxic Stress and Functions Independently of p53
p53 and NFB are two key effectors in the chemotherapy-induced genotoxic response. Although p53 is a universal inducer of… (More)
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2001
2001
MRI Phenotype Is Associated With Response to Doxorubicin and Cyclophosphamide Neoadjuvant Chemotherapy in Stage III Breast Cancer
Background: The preferred management for women with stage II or locally advanced breast cancer (LABC) is neoadjuvant chemotherapy… (More)
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