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response to amino acid starvation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… Expand
National Institutes of Health

Papers overview

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2016
2016
eIF4A inactivates TORC1 in response to amino acid starvation
Amino acids regulate TOR complex 1 (TORC1) via two counteracting mechanisms, one activating and one inactivating. The presence of… Expand
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Highly Cited
2013
Highly Cited
2013
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
In response to different environmental stresses, eIF2α phosphorylation represses global translation coincident with preferential… Expand
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Highly Cited
2010
Highly Cited
2010
DAP1, a Novel Substrate of mTOR, Negatively Regulates Autophagy
Autophagy, a catabolic process responsible for the degradation of cytosolic components, is upregulated when nutrient supplies are… Expand
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Highly Cited
2009
Highly Cited
2009
The ObgE/CgtA GTPase influences the stringent response to amino acid starvation in Escherichia coli
The stringent response is important for bacterial survival under stressful conditions, such as amino acid starvation, and is… Expand
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Highly Cited
2009
Highly Cited
2009
The hnRNA-Binding Proteins hnRNP L and PTB Are Required for Efficient Translation of the Cat-1 Arginine/Lysine Transporter mRNA during Amino Acid Starvation
ABSTRACT The response to amino acid starvation involves the global decrease of protein synthesis and an increase in the… Expand
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Highly Cited
2008
Highly Cited
2008
The global, ppGpp‐mediated stringent response to amino acid starvation in Escherichia coli
The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed in favour of transcription of amino… Expand
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Highly Cited
2005
Highly Cited
2005
GCN2 whets the appetite for amino acids.
In response to amino acid starvation, the kinase GCN2 in yeast activates amino acid biosynthesis. Two recent studies (Maurin et… Expand
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Highly Cited
2002
Highly Cited
2002
Tsc tumour suppressor proteins antagonize amino-acid–TOR signalling
Target of Rapamycin (TOR) mediates a signalling pathway that couples amino acid availability to S6 kinase (S6K) activation… Expand
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Highly Cited
2002
Highly Cited
2002
DksA affects ppGpp induction of RpoS at a translational level.
The RpoS sigma factor (also called sigmaS or sigma38) is known to regulate at least 50 genes in response to environmental sources… Expand
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Highly Cited
1997
Highly Cited
1997
The gene encoding the major proline transporter of Aspergillus nidulans is upregulated during conidiospore germination and in response to proline induction and amino acid starvation
In Aspergillus nidulans a highly specific l‐proline transporter is encoded by the prnB gene which is tightly linked to all other… Expand
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