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response to 1-oleoyl-sn-glycerol 3-phosphate

Known as: response to lysophosphatidic acid, response to oleoyl-L-alpha-lysophosphatidic acid, response to LPA 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Integrin α6β4 Controls the Expression of Genes Associated with Cell Motility, Invasion, and Metastasis, Including S100A4/Metastasin*
The integrin α6β4 is associated with carcinoma progression by contributing to apoptosis resistance, invasion, and metastasis, due… Expand
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Highly Cited
2002
Highly Cited
2002
Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells.
Vasodilator actions of insulin are mediated by signaling pathways involving phosphatidylinositol 3-kinase (PI 3-kinase) and Akt… Expand
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Highly Cited
2001
Highly Cited
2001
Regulation of Tight Junction Permeability and Occludin Phosphorylation by RhoA-p160ROCK-dependent and -independent Mechanisms*
In epithelial and endothelial cells, tight junctions regulate the paracellular permeability of ions and proteins. Disruption of… Expand
Highly Cited
2000
Highly Cited
2000
Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate.
Two G protein-coupled receptors (Edg-2) and (Edg-4) for the lysolipid phosphoric acid mediator lysophosphatidic acid have been… Expand
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Highly Cited
1998
Highly Cited
1998
Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK.
Phosphoinositide 3-kinases (PI3Ks) activate protein kinase PKB (also termed Akt), and PI3Kgamma activated by heterotrimeric… Expand
Highly Cited
1998
Highly Cited
1998
Edg-2/Vzg-1 Couples to the Yeast Pheromone Response Pathway Selectively in Response to Lysophosphatidic Acid*
We have functionally expressed the human cDNA encoding the putative lysophosphatidic acid (LPA) receptor Edg-2 (Vzg-1) in… Expand
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Highly Cited
1998
Highly Cited
1998
Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization.
Mobilization of intracellular Ca2+ is a critical cellular response to lysophosphatidic acid (LPA) in many cell types. Recent… Expand
Highly Cited
1997
Highly Cited
1997
Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
A cDNA homologous to that encoding sheep Edg2 protein was cloned from a human lung cDNA library. The full-length sequence encodes… Expand
Highly Cited
1994
Highly Cited
1994
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
Stimulation of Gi-coupled receptors leads to the activation of mitogen-activated protein kinases (MAP kinases). In several cell… Expand
Highly Cited
1992
Highly Cited
1992
Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase.
The overall fatty acid composition of leaf lipids in a mutant of Arabidopsis thaliana was characterized by reduced levels of… Expand
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