FAQ

response to 1-oleoyl-sn-glycerol 3-phosphate

Known as: response to lysophosphatidic acid, response to oleoyl-L-alpha-lysophosphatidic acid, response to LPA 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2016
051019902016

Papers overview

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Highly Cited
2009
Highly Cited
2009
Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin.
The integrin alpha6beta4 is associated with carcinoma progression by contributing to apoptosis resistance, invasion, and… (More)
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2006
2006
Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are bioactive lipid signaling molecules implicated in tumor… (More)
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Highly Cited
2002
Highly Cited
2002
Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation.
Transactivation of the epidermal growth factor receptor (EGFR) represents the paradigm for cross-talk between G protein-coupled… (More)
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Highly Cited
2001
Highly Cited
2001
Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).
Vasodilator actions of insulin are mediated by activation of endothelial nitric-oxide synthase (eNOS) and subsequent production… (More)
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2001
2001
Insulin-stimulated Activation of eNOS Is Independent of Ca but Requires Phosphorylation
Vasodilator actions of insulin are mediated by activation of endothelial nitric-oxide synthase (eNOS) and subsequent production… (More)
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Highly Cited
1999
Highly Cited
1999
Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells.
Lysophosphatidic acid (LPA) is present at high concentrations in ascites from ovarian cancer patients and has potent mitogenic… (More)
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1999
1999
The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation.
In Rat-1 fibroblasts nonmitogenic doses of lysophosphatidic acid (LPA) stimulate a transient activation of mitogen-activated… (More)
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Highly Cited
1997
Highly Cited
1997
Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid.
Sphingosine 1-phosphate (Sph-1-P) has been implicated as an intracellular second messenger in many studies. We investigated the… (More)
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Highly Cited
1997
Highly Cited
1997
Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
A cDNA homologous to that encoding sheep Edg2 protein was cloned from a human lung cDNA library. The full-length sequence encodes… (More)
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Highly Cited
1996
Highly Cited
1996
Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
Neocortical neuroblast cell lines were used to clone G-protein-coupled receptor (GPCR) genes to study signaling mechanisms… (More)
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