• Publications
  • Influence
Mitochondrial dynamics regulates migration and invasion of breast cancer cells
Mitochondria are highly dynamic and undergo constant fusion and fission that are essential for maintaining physiological functions of cells. Although dysfunction of mitochondria has been implicatedExpand
  • 328
  • 19
  • PDF
Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1
Mutations in the amyloid precursor protein (APP) cause early-onset Alzheimer's disease (AD), but the only genetic risk factor for late-onset AD is the varepsilon4 allele of apolipoprotein E (apoE), aExpand
  • 313
  • 19
Cholesterol metabolism and homeostasis in the brain
Cholesterol is an essential component for neuronal physiology not only during development stage but also in the adult life. Cholesterol metabolism in brain is independent from that in peripheralExpand
  • 204
  • 12
  • PDF
Effects of pollution sources and soil properties on distribution of polycyclic aromatic hydrocarbons and risk assessment.
  • J. Zhang, J. Yang, +5 authors J. Dai
  • Chemistry, Environmental Science
  • The Science of the total environment
  • 1 October 2013
In this study, the concentrations of polycyclic aromatic hydrocarbons (PAHs) in soil profiles and the soil properties were analyzed in Hunpu, a typical wastewater irrigation area, northeast of China.Expand
  • 58
  • 12
Heparan Sulphate Proteoglycan and the Low-Density Lipoprotein Receptor-Related Protein 1 Constitute Major Pathways for Neuronal Amyloid-β Uptake
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder in which the aggregation and deposition of amyloid-β (Aβ) peptides in the brain are central to its pathogenesis.Expand
  • 126
  • 11
Flavones and flavonols play distinct critical roles during nodulation of Medicago truncatula by Sinorhizobium meliloti.
Flavonoids play critical roles in legume-rhizobium symbiosis. However, the role of individual flavonoid compounds in this process has not yet been clearly established. We silenced differentExpand
  • 184
  • 11
Lower Plasma Levels and Accelerated Clearance of High Density Lipoprotein (HDL) and Non-HDL Cholesterol in Scavenger Receptor Class B Type I Transgenic Mice*
Recent studies have indicated that the scavenger receptor class B type I (SR-BI) may play an important role in the uptake of high density lipoprotein (HDL) cholesteryl ester in liver andExpand
  • 236
  • 10
Protein tyrosine kinase Syk in mast cell signaling.
The tyrosine kinase Syk is essential for signaling from FcrepsilonRI in mast cells. The Src homology domain mediated binding of Syk to the phosphorylated immunoreceptor tyrosine-based motif (ITAM) ofExpand
  • 132
  • 10
Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and Neurogenesis
The procedure of neurogenesis has made numerous achievements in the past decades, during which various molecular biomarkers have been emerging and have been broadly utilized for the investigation ofExpand
  • 102
  • 10
  • PDF
GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis
Littlewood-Evans et al. demonstrate that extracellular succinate leads to the propagation of inflammatory macrophage activation, providing translational evidence to support the development of GPR91Expand
  • 138
  • 9