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replication fork protection

Any process that prevents the collapse of stalled replication forks. [GOC:vw, PMID:14560029]
National Institutes of Health

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Broader (1)

replication fork maintenance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
BRCA1 Phosphorylation and Isomerization Enhances Replication Fork Protection.
BRCA1-BARD1 promotes fork protection independently of the canonical BRCA1-PALB2-BRCA2-RAD51 pathway. 
2019
2019
Characterization of a potent dominant negative mutant variant of Rad51 in Ustilago maydis.
2019
2019
Single-Molecule DNA Fiber Analyses to Characterize Replication Fork Dynamics in Living Cells.
Understanding the molecular dynamics of DNA replication in vivo has been a formidable challenge requiring the development of… 
2019
2019
Abstract 368A: Functional assessment of DNA damage repair defects and the anti-tumor immune response in high grade serous ovarian cancers using patient-derived organoids
Patients with high grade serous ovarian cancer (HGSC) have limited additional therapeutic options beyond traditional carboplatin… 
Review
2018
Review
2018
Loss of Cohesin Subunit Rec8 Switches Rad51 Mediator Dependence in Resistance to Formaldehyde Toxicity in Ustilago maydis
DNA–protein cross-links (DPCs) are frequently occurring lesions that provoke continual threats to the integrity of the genome by… 
2017
2017
PARPi focus the spotlight on replication fork protection in cancer
PARP inhibitors (PARPi) kill BRCA1/2-mutated cancers, which become resistant when DNA repair functions are restored. Now, MUS81… 
Review
2017
Review
2017
Chabner Colloquium: Answering the Big Questions in Cancer Research & 2017 STO Annual Meeting
1 – PARP Inhibitor Resistance and Acquired Vulnerability in Ovarian Cancer ALAN D’ANDREA, SUSAN F. SMITH CENTER FOR WOMEN’S… 
2014
2014
Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
2013
2013
A Mutation in the FHA Domain of Coprinus cinereus Nbs1 Leads to Spo11-Independent Meiotic Recombination and Chromosome Segregation
Nbs1, a core component of the Mre11-Rad50-Nbs1 complex, plays an essential role in the cellular response to DNA double-strand… 
2011
2011
Division of labor of the replication fork protection complex subunits in sister chromatid cohesion and Chk1 activation
Sister chromatid cohesion (SCC) is established during S phase near the replication fork. The cohesin complex, which has a major… 
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