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regulation of telomerase activity
Known as:
telomerase regulator
Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
biological control
telomerase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The PinX1/NPM interaction associates with hTERT in early-S phase and facilitates telomerase activation
S. Ho
,
R. Jin
,
Derek Hang-Cheong Cheung
,
Jun-jian Huang
,
P. Shaw
Cell & Bioscience
2019
Corpus ID: 189763707
Telomere maintenance is an important factor in tumorigenesis. PinX1 is a potent telomerase regulator which also involves in…
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2017
2017
Nucleophosmin Interacts with PIN2/TERF1-interacting Telomerase Inhibitor 1 (PinX1) and Attenuates the PinX1 Inhibition on Telomerase Activity
Derek Hang-Cheong Cheung
,
S. Ho
,
+5 authors
P. Shaw
Scientific Reports
2017
Corpus ID: 15857999
Telomerase activation and telomere maintenance are critical for cellular immortalization and transformation. PIN2/TERF1…
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Highly Cited
2011
Highly Cited
2011
Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast
J. Greenwood
,
J. Cooper
Nucleic Acids Research
2011
Corpus ID: 5933799
While telomere repeat-containing non-coding RNA has been identified in a variety of eukaryotes, its biological role is not yet…
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Highly Cited
2011
Highly Cited
2011
The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation
Hui-Yong Lian
,
E. D. Robertson
,
+7 authors
A. Donaldson
Molecular Biology of the Cell
2011
Corpus ID: 16932186
Ku controls telomere replication timing. We test the mechanism and find that Ku does not bind telomere-proximal origins directly…
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Highly Cited
1999
Highly Cited
1999
Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells.
A. Cuthbert
,
J. Bond
,
+7 authors
R. Newbold
Journal of the National Cancer Institute
1999
Corpus ID: 3059009
BACKGROUND Activation of the enzyme telomerase, which has been associated with cellular immortality, may constitute a key step in…
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