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queuine

Known as: 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-, (1S-(1alpha,4beta,5beta))-, Q base, base Q 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Guanine
analogs & derivatives

Papers overview

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2008
2008
Queuine mediated inhibition in phosphorylation of tyrosine phosphoproteins in cancer
Protein phosphorylation or dephosphorylation is the most important regulatory switch of signal transduction contributing to… 
2004
2004
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer.
2003
2003
tRNA-guanine transglycosylase from E. coli: a ping-pong kinetic mechanism is consistent with nucleophilic catalysis.
1994
1994
Altered queuine modification of transfer RNA involved in the differentiation of human K562 erythroleukemia cells in the presence of distinct differentiation inducers.
Altered queuine modification of tRNA has been correlated to neoplasia and cell differentiation, but much of the existing evidence… 
1993
1993
Overproduction and purification of native and queuine-lacking Escherichia coli tRNA(Asp). Role of the wobble base in tRNA(Asp) acylation.
Escherichia coli tRNA(Asp) was overproduced in E. coli up to 15-fold from a synthetic tRNA(Asp) gene placed in a plasmid under… 
1990
1990
Queuine modulates growth of HeLa cells depending on oxygen availability.
HeLa cells can be grown in media supplemented with horse serum that is lacking the nutrient factor queuine. The addition of 1 X… 
Review
1988
Review
1988
The nutrient factor queuine: biosynthesis, occurrence in transfer RNA and function.
Queuine, 7-(( (4,5-cis-dihydroxy-2-cyclopenten-1-yl)-amino]-methyl)-7-deazagu ani ne is synthesized de novo only in eubacteria… 
Highly Cited
1984
Highly Cited
1984
Evidence that the nucleic acid base queuine is incorporated intact into tRNA by animal cells.
Queuine (the base of queuosine, Q) catalytically reduced with tritium or deuterium yields a derivative in which the proton at C-8… 
1983
1983
Site‐directed in vitro replacement of nucleosides in the anticodon loop of tRNA: application to the study of structural requirements for queuine insertase activity.
We have investigated the specificity of the enzymes Q‐insertase and mannosyl‐Q transferase that replace the guanosine at position… 
1980
1980
Reversed-phase boronate chromatography for the separation of O-methylribose nucleosides and aminoacyl-tRNAs.
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