pyruvate oxidation

The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate. [MetaCyc:PYRUVOX-PWY]
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Cancer cells are typically subject to profound metabolic alterations, including the Warburg effect wherein cancer cells oxidize a… (More)
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Highly Cited
2012
Highly Cited
2012
Pyruvate constitutes a critical branch point in cellular carbon metabolism. We have identified two proteins, Mpc1 and Mpc2, as… (More)
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Highly Cited
2011
Highly Cited
2011
To fulfill the bioenergetic and biosynthetic demand of proliferation, T cells reprogram their metabolic pathways from fatty acid… (More)
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Highly Cited
2010
Highly Cited
2010
The traditional view is that cancer cells predominately produce ATP by glycolysis, rather than by oxidation of energy-providing… (More)
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Highly Cited
2002
Highly Cited
2002
The prevailing concept of the heart’s response to changes in its environment is a complex network of interconnecting signal… (More)
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Highly Cited
2001
Highly Cited
2001
Pyruvate dehydrogenase kinase isoform 4 (PDK4) is upregulated by starvation in many tissues of the body during starvation. This… (More)
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Review
1997
Review
1997
The effects of diabetes on myocardial metabolism are complex in that they are tied to the systemic metabolic abnormalities of the… (More)
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Review
1997
Review
1997
It is now clear that the availability of different metabolic substrates can have a profound influence on the extent of damage… (More)
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Highly Cited
1996
Highly Cited
1996
OBJECTIVE The purpose of this study was to quantitate the derangements in intermediary carbohydrate metabolism and oxygen use in… (More)
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Highly Cited
1974
Highly Cited
1974
1. Monochloroacetate, dichloroacetate, trichloroacetate, difluoroacetate, 2-chloropropionate, 2,2'-dichloropropionate and 3… (More)
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