pyruvate kinase activity

Known as: ATP:pyruvate 2-O-phosphotransferase activity, phosphoenol transphosphorylase activity, phosphoenolpyruvate kinase activity 
Catalysis of the reaction: ATP + pyruvate = ADP + phosphoenolpyruvate. [EC:2.7.1.40]
National Institutes of Health

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Broader (1)

Glycolysis
negative regulation of pyruvate kinase activitypositive regulation of pyruvate kinase activity

Papers overview

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2008
2008
Glycolytic enzyme expression and pyruvate kinase activity in cultured fibroblasts from type 1 diabetic patients with and without nephropathy.
Since type 1 diabetes mellitus (T1DM) patients with nephropathy (DN+) are insulin-resistant, we aimed to identify (new) potential… (More)
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2000
2000
Changes in the infectivity, pyruvate kinase activity, acid phosphatase activity and P-glycoprotein expression in glibenclamide-resistant Leishmania mexicana
We previously demonstrated susceptibility of Leishmania sp. to glibenclamide, a K+-ATP transport blocker which interacts with… (More)
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Highly Cited
1999
Highly Cited
1999
Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein.
We report here that the E7 oncoprotein encoded by the oncogenic human papillomavirus (HPV) type 16 binds to the glycolytic enzyme… (More)
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1995
1995
1,25-dihydroxyvitamin D3 inhibits proliferation of IMR-90 human fibroblasts and stimulates pyruvate kinase activity in confluent-phase cells.
This study tested the hypothesis that 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) plays a role in regulating some aspects of… (More)
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1992
1992
Insulin regulation of pyruvate kinase activity in isolated adipocytes. Crucial role of glucose and the hexosamine biosynthesis pathway in the expression of insulin action.
We recently identified glutamine:fructose-6-phosphate amidotransferase (GFAT) as an insulin-regulated enzyme in adipocytes… (More)
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1985
1985
Activation of glycolysis by insulin with a sequential increase of the 6-phosphofructo-2-kinase activity, fructose-2,6-bisphosphate level and pyruvate kinase activity in cultured rat hepatocytes.
The involvement of 6-phosphofructo-2-kinase, fructose 2,6-bisphosphate [Fru(2,6)P2] and pyruvate kinase in the insulin-dependent… (More)
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1979
1979
Adrenergic control of glycolysis and pyruvate kinase activity in hepatocytes from young and old rats.
The influence of various adrenergic agonists and antagonists on pyruvate kinase activity and lactate production from endogenous… (More)
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1976
1976
Hormonal control of pyruvate kinase activity and of gluconeogenesis in isolated hepatocytes.
Treatment of isolated rat hepatocytes with saturating concentrations of glucagon caused several modifications properties of… (More)
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1975
1975
Effect of lipopolysaccharide and lipid A on mouse liver pyruvate kinase activity.
Several investigators have reported lipid A as the biologically active unit in the lipopolysaccharide (LPS) molecule. To… (More)
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1972
1972
The role of mitochondria in modifying calcium-sensitive cytoplasmic metabolic activities. Modification of pyruvate kinase activity.
1. The modification of pyruvate kinase activity in vitro was examined by altering the environmental [Mg(2+)]/[Ca(2+)] ratio with… (More)
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