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Paradoxical Influence of Calcium Ions on the Permeability of the Cell Membranes of the Isolated Rat Heart
IN the course of an investigation of the specificity of acetoacetate which causes electromechanical dissociation1 we found that pyruvate also inhibited contractility of the rat heart and dog heart,Expand
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Fatty acid activation: specificity, localization, and function.
Publisher Summary This chapter discusses fatty acid activation. Most cells can metabolize fatty acids. The most important pathways are β-oxidation to acetyl-CoA; esterification with glycerolExpand
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The activation and oxidation of octanoate and palmitate by rat skeletal muscle mitochondria.
Abstract 1. 1. Rat skeletal muscle mitochondria can oxidize octanoate just as well as palmitate. The oxidation of both fatty acids is strongly carnitine dependent, which indicates that the fatty acidExpand
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Secretion of triacylglycerol hydrolase activity by isolated parenchymal rat liver cells
More than 80% of the neutral triacylglycerol hydrolase activity of rat liver can be released from the liver by heparin [ 11. Isolation of parenchymal or nonparenchymal liver cells with collagenaseExpand
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Effect of dietary fat composition on the metabolism of triacylglycerol-rich plasma lipoproteins in the postprandial phase in meal-fed rats.
Rats conditioned to eating fixed-size meals (meals at 7 AM and 7 PM), consuming diets rich in palm oil or sunflower seed oil, were used to study the metabolism of chylomicrons and hepatic very lowExpand
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Properties of phosphatidate phosphohydrolase and diacylglycerol acyltransferase activities in the isolated rat heart. Effect of glucagon, ischaemia and diabetes.
Myocardial triacylglycerol hydrolysis is subject to product inhibition. After hydrolysis of endogenous triacylglycerols, the main proportion of the liberated fatty acids is re-esterified toExpand
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Carnitine requirement of vascular endothelial and smooth muscle cells in imminent ischemia
Vascular endothelial and -smooth muscle cells have been shown to use fatty acids as substrates for oxidative phosphorylation. Endothelial cells are more vulnerable to oxidative stress than muscleExpand
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Accumulation and excretion of long-chain acylcarnitine by rat hearts; studies with aminocarnitine.
During Langendorff perfusion of rat heart with aminocarnitine, long-chain acylcarnitine (LCAC) accumulates in heart cells, from which it is excreted by the heart. The heart function remains intactExpand
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Hormonal control of cardiac lipolysis by glyco(geno)lysis.
The importance of the glucose/fatty acid cycle in the control of cardiac lipolysis is emphasized by the following observations. Addition of the glycogen debranching inhibitor deoxynojirimycin or anExpand
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Coronary vasodilation by fatty acids.
Fatty acids increase the coronary flow rate of rat hearts, perfused according to the Langendorff technique. Long-chain and medium-chain fatty acids are more effective vasodilators than short-chainExpand
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