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pyruvamide

National Institutes of Health

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Pyruvates

Papers overview

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2010
2010
Mass spectrometric characterization of modifications to angiotensin II by lipid peroxidation products, 4-oxo-2(E)-nonenal and 4-hydroxy-2(E)-nonenal.
The octapeptide angiotensin II (Ang II; Asp(1)-Arg(2)-Val(3)-Tyr(4)-Ile(5)-His(6)-Pro(7)-Phe(8)) is the primary active hormone of… 
2006
2006
Function of a conserved loop of the beta-domain, not involved in thiamin diphosphate binding, in catalysis and substrate activation in yeast pyruvate decarboxylase.
The X-ray crystal structure of pyruvamide-activated yeast pyruvate decarboxylase (YPDC) revealed a flexible loop spanning… 
1993
1993
Role of cysteines in the activation and inactivation of brewers' yeast pyruvate decarboxylase investigated with a PDC1-PDC6 fusion protein.
Possible roles of the Cys side chains in the activation and inactivation mechanisms of brewers' yeast pyruvate decarboxylase were… 
1993
1993
Catalysis of acetoin formation by brewers' yeast pyruvate decarboxylase isozymes.
Catalysis of C(alpha)-proton transfer from 2-(1-hydroxyethyl)thiamin diphosphate (HETDP) by pyruvate decarboxylase isozymes (PDC… 
1992
1992
Resolution of brewer's yeast pyruvate decarboxylase into multiple isoforms with similar subunit structure and activity using high-performance liquid chromatography.
1990
1990
An X‐ray solution scattering study of the cofactor and activator induced structural changes in yeast pyruvate decarboxylase (PDC)
1988
1988
The functional role of thiol groups of pyruvate decarboxylase from brewer's yeast.
Pyruvate decarboxylase purified from brewer's yeast has been modified by the thiol specific reagents 4-hydroxy-mercuri-benzoate… 
1983
1983
Active site directed irreversible inactivation of brewers' yeast pyruvate decarboxylase by the conjugated substrate analogue (E)-4-(4-chlorophenyl)-2-oxo-3-butenoic acid: development of a suicide…
(E)-4-(4-Chlorophenyl)-2-oxo-3-butenoic acid (CPB) was found to irreversibly inactivate brewers' yeast pyruvate decarboxylase… 
Highly Cited
1974
Highly Cited
1974
Identification of radioproducts resulting from the breakage of thymine moiety by gamma irradiation of E. coli DNA in an aerated aqueous solution.
TEOULE, R., BONICEL, A., BERT, C., CADET, J., AND POLVERELLI, M., Identification of Radioproducts Resulting from the Breakage of… 
1973
1973
The influence of steric and electronic parameters on the substrate behavior of -oxo acids to yeast pyruvate decarboxylase.
The Michaelis constants of yeast pyruvate decarboxylase at full substrate activation and the maximum decarboxylation rates were… 
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