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pyrodifenium bromide

Known as: PRIFINIUM BROMIDE, Pyrrolidinium, 3-(diphenylmethylene)-1,1-diethyl-2-methyl-, bromide, padrin 
National Institutes of Health

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Pyrrolidines
prifinium

Papers overview

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2007
2007
Anti-spasmodic effect of prifinium bromide on the proximal and distal colon in patients with diverticular disease
SummaryIn 5 patients with diverticular disease, colonie motilities of the proximal and distal colon were recorded using the ERBI… 
Review
1994
Review
1994
[The clinical pharmacological profile of pinaverium bromide].
Pinaverium bromide is a locally acting spasmolytic agent of the digestive tract. Its mechanism of action relies upon inhibition… 
1985
1985
Studies on papillary function and effect of prifinium bromide and other antispasmodics on motility of the papillary region (sphincter of Oddi) in humans.
We determined endoscopically the motility of the papillary region in humans, using a pressure sensor devised in our department… 
1984
1984
Effect of antispasmodic drugs on colonic motility. Part I: Laboratory study of the dog.
The inhibitory effect of five antispasmodic preparations, prifinium bromide, hyoscine butylbromide, propinox, trimebutine maleate… 
1984
1984
Effect of antispasmodic drugs on the colonic motility. Part II: Clinical study in man.
Four antispasmodic preparations (prifinium bromide, propinox, trimebutine maleate and phloroglucinol + trimethylphloroglucinol… 
1982
1982
High-performance liquid chromatographic determination of prifinium quaternary ammonium ion in human serum and urine.
1980
1980
Studies on antispasmodics. V. Synthesis and anticholinergic activity of N-alkyl 1- and 2-diarylmethylene-indolizidinium bromides.
In a search for new antispasmodics, we have synthesized N-alkyl 2- and 1-diarylmethyleneindolizidinium bromides (6-13), which can… 
1979
1979
Prifinium bromide in the treatment of the irritable colon syndrome
1970
1970
Studies on the ratio of equipotent oral and subcutaneous doses in man of prifinium bromide, a new synthetic spasmolytic.
1967
1967
Pharmacological activities of 1,1-diethyl-2-methyl-3-diphenylmethylenepyrrolidinium bromide (pyrodifenium bromide).
In recent years there have been a great number of compounds synthesized for their atropine-like effect. Recently a new class of… 
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