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pyrithione

Known as: 1-hydroxypyridine-2-thione, 1-hydroxy- 2(1H)-pyridinethione, N-hydroxypyridine-2-thione 
A fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, pyrithione… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (4)

68Ga-mercaptopyridine-N-oxideOmadinesodium pyridinethionezinc pyrithione

Broader (3)

Antifungal AgentsPyridinesThiones
Pyrithione Sodiumselenium sulfide 10 MG/ML Medicated Shampoo [Selsun Blue]zinc pyrithione 10 MG/ML Medicated Shampoozinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]

Papers overview

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Highly Cited
2009
Highly Cited
2009
3-nitro-2-pyridinesulfenyl (Npys) group. A novel selective protecting group which can be activated for peptide bond formation.
The novel 3-nitro-2-pyridinesulfenyl (Npys) group, which is useful for the protection and the activation of amino and hydroxyl… 
2003
2003
Characterisation of zinc uptake into rat cultured cerebrocortical oligodendrocyte progenitor cells
2002
2002
Elevated intracellular zinc and altered proton homeostasis in forebrain neurons
Highly Cited
2000
Highly Cited
2000
Astrocytes Are More Resistant Than Neurons to the Cytotoxic Effects of Increased [Zn2+]i
Increased intracellular free Zn(2+) ([Zn(2+)](i)) is toxic to neurons. Glia are more resistant to Zn(2+)-mediated toxicity… 
1992
1992
In vitro effects of three iron chelators on mitogen-activated lymphocytes: identification of differences in their mechanisms of action.
1991
1991
Role for zinc in a cellular response mediated by protein kinase C in human B lymphocytes.
1988
1988
The influence of pyrithione on the growth of micro-organisms.
Pyrithione was active against a range of micro-organisms, the most resistant being Gram-negative bacteria. The growth curves for… 
1986
1986
Cytotoxic effects of the lipophilic iron chelator omadine
1985
1985
Evaluation of indium-111-2-mercaptopyridine-N-oxide for labeling leukocytes in plasma: a kit preparation.
Pure neutrophils, lymphocytes, and mixed leukocytes have been labeled in vitro with 111ln chelated to a nontoxic, water soluble… 
1975
1975
Aspects of the photochemical behaviour of 1-hydroxypyridine-2-thione.
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