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pyrithione

Known as: 1-hydroxypyridine-2-thione, 1-hydroxy- 2(1H)-pyridinethione, N-hydroxypyridine-2-thione 
A fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, pyrithione… 
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (4)

68Ga-mercaptopyridine-N-oxideOmadinesodium pyridinethionezinc pyrithione

Broader (3)

Antifungal AgentsPyridinesThiones
Pyrithione Sodiumselenium sulfide 10 MG/ML Medicated Shampoo [Selsun Blue]zinc pyrithione 10 MG/ML Medicated Shampoozinc pyrithione 10 MG/ML Medicated Shampoo [Head & Shoulders]

Papers overview

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Highly Cited
2011
Highly Cited
2011
Clioquinol induces autophagy in cultured astrocytes and neurons by acting as a zinc ionophore
Highly Cited
2009
Highly Cited
2009
3-nitro-2-pyridinesulfenyl (Npys) group. A novel selective protecting group which can be activated for peptide bond formation.
The novel 3-nitro-2-pyridinesulfenyl (Npys) group, which is useful for the protection and the activation of amino and hydroxyl… 
Highly Cited
2008
Highly Cited
2008
Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitiol against Picornavirus Infections
ABSTRACT We have discovered two metal ion binding compounds, pyrithione (PT) and hinokitiol (HK), that efficiently inhibit human… 
Highly Cited
2008
Highly Cited
2008
Insights into Zn2+ homeostasis in neurons from experimental and modeling studies.
To understand the mechanisms of neuronal Zn2+ homeostasis better, experimental data obtained from cultured cortical neurons were… 
Highly Cited
2006
Highly Cited
2006
Flow cytometric measurement of labile zinc in peripheral blood mononuclear cells.
2003
2003
Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death
2003
2003
Characterisation of zinc uptake into rat cultured cerebrocortical oligodendrocyte progenitor cells
Highly Cited
1998
Highly Cited
1998
Diverse effects of metal chelating agents on the neuronal cytotoxicity of zinc in the hippocampus
1996
1996
Photolysis of N-hydroxpyridinethiones: a new source of hydroxyl radicals for the direct damage of cell-free and cellular DNA.
N-Hydroxypyridine-2-thione (2-HPT), known to release hydroxyl radicals on irradiation with visible light, and two related… 
Highly Cited
1965
Highly Cited
1965
SAFETY EVALUATION OF ZINC 2-PYRIDINETHIOL 1-OXIDE IN A SHAMPOO FORMULATION.
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